Résultats: 681

    Summary for patients: pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults

    Ann. intern. med; 176 (2), 2023
    Osteoporosis is a disease, common in older age, that makes your bones weaker and can lead to a fracture. People with previous fractures and those who have other risk factors for fractures, including family history of fractures, vitamin D deficiency or low calcium intake, smoking, excessive alcohol intake...

    Maribavir for treating refractory cytomegalovirus infection after transplant

    Evidence-based recommendations on maribavir (Livtencity) for cytomegalovirus infection in adults after transplant. Commercial arrangement There is a simple discount patient access scheme for maribavir. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisat...

    Angiotensin II for treating vasosuppressor-resistant hypotension caused by septic or distributive shock (terminated appraisal)

    NICE is unable to make a recommendation on angiotensin II for treating vasosuppressor-resistant hypotension caused by septic or distributive shock. This is because Paion AG did not provide an evidence submission. We will review this decision if the company decides to make a submission....

    Lenvatinib with pembrolizumab for untreated advanced renal cell carcinoma

    Evidence-based recommendations on lenvatinib (Kisplyx) with pembrolizumab (Keytruda) for untreated advanced renal cell carcinoma in adults. Commercial arrangements There is a simple discount patient access scheme for lenvatinib and a commercial access agreement for pembrolizumab. NHS organisations can g...

    Mobocertinib for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy

    Evidence-based recommendations on mobocertinib (EXKIVITY) for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy in adults. Commercial arrangement There is a simple discount patient access scheme for mobocertinib. NHS organisations ca...

    Upadacitinib for treating moderately to severely active ulcerative colitis

    Evidence-based recommendations on upadacitinib (Rinvoq) for treating moderately to severely active ulcerative colitis in adults. Commercial arrangement There is a simple discount patient access scheme for upadacitinib. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. ...

    The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder

    The American Society of Addiction Medicine (ASAM) and the American Academy of Addiction Psychiatry (AAAP) developed this Clinical Practice Guideline on the Management of Stimulant Use Disorder (hereafter referred to as the Guideline) to provide evidence-based strategies and standards of care for the trea...

    ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update

    Ann. rheum. dis; 82 (1), 2023
    To update the Assessment of SpondyloArthritis international Society (ASAS)-EULAR recommendations for the management of axial spondyloarthritis (axSpA). Following the EULAR Standardised Operating Procedures, two systematic literature reviews were conducted on non-pharmacological and pharmacological treatm...

    Guía de Práctica Clínica Nacional para el tratamiento con potenciadores y moduladores del Regulador de la Conductancia Transmembrana de la Fibrosis Quística

    La fibrosis quística (FQ) es una enfermedad crónica y progresiva, de origen genético, de herencia autosómica recesiva, causada por mutaciones en el gen que codifica para la proteína reguladora de la conductancia transmembrana de la fibrosis quística (CFTR su sigla del inglés Cystic Fibrosis Transm...

    Guía de práctica clínica para la detección oportuna, diagnóstico, tratamiento y seguimiento de Linfoma No Hodgkin en niños, niñas y adolescentes. Guía completa. Actualización parcial, 2023

    El Instituto de Evaluación Tecnológica en Salud (IETS) bajo el liderazgo del Ministerio de Salud y Protección Social (MSPS) inició el proceso de actualización de la “Guía de Práctica Clínica para el diagnóstico y tratamiento de Linfoma de Hodgkin (LH) y Linfoma no Hodgkin (LNH) en niños, niñ...