Athanazio, Rodrigo Abensur;
Tanni, Suzana Erico;
Ferreira, Juliana;
Fuccio, Marcelo de;
Marostica, Paulo José Cauduro;
Ferreira, Juliana;
Dalcin, Paulo de Tarso Roth;
Esposito, Concetta;
Canan, Mariane Gonçalves Martynychen;
Coelho, Liana Sousa;
Firmida, Mônica de Cássia;
Almeida, Marina Buarque de;
Monte, Luciana de Freitas Velloso;
Souza, Edna Lúcia;
Pinto, Leonardo Araujo;
Rached, Samia Zahi;
Oliveira, Verônica Stasiak Bednarczuk de;
Riedi, Carlos Antonio;
Silva Filho, Luiz Vicente Ribeiro Ferreira da.
A fibrose cística (FC) é uma doença genética que resulta em disfunção da proteína
reguladora de condutância transmembrana da FC (CFTR), que é um canal de cloro e
bicarbonato expresso na porção apical de células epiteliais de diversos órgãos. A
disfunção dessa proteína resulta em manifest...
Amer, Marwa;
Alshahrani, Mohammed;
Arabi, Yaseen;
Al‑jedai, Ahmed;
Alshaqaq, Hassan M;
Al‑Sharydah, Abdulaziz;
Al‑Suwaidan, Faisal A;
Aljehani, Hosam;
Nouh, Thamer;
Mashbari, Hassan;
Tarazan, Nehal;
Alqahtani, Saad;
Tashkandi, Wail;
Maghrabi, Khalid;
Albugami, Muneerah;
Albugami, Muneerah;
Hashim, Samaher;
Alsubaie, Norah M;
Alsenani, Mohammad;
Algethamy, Haifa;
Alshammari, Thamir M;
Alaklabi, Ali;
Ismail, Nadia;
Altawil, Esraa S;
Elhazmi, Alyaa;
Nahhas, Ahmed;
Aljuaid, Maha;
Alsadoon, Naif;
Binbraik, Yasser;
Yuan, Yuhong;
Alhazzani, Waleed.
To develop evidence-based clinical practice guidelines on venous thromboembolism (VTE) prevention in adults with trauma in inpatient settings. The Saudi Critical Care Society (SCCS) sponsored guidelines development and included 22 multidisciplinary panel members who completed conflict-of-interest forms. ...
This guideline covers the diagnosis and management of type 1 and type 2 diabetes in children and young people aged under 18. The guideline recommends how to support children and young people and their families and carers to maintain tight control of blood glucose to reduce the long-term risks associated ...
People with BRCA mutation-positive HER2‑negative high-risk early breast cancer usually have chemotherapy followed by surgery (neoadjuvant chemotherapy), or surgery followed by chemotherapy (adjuvant chemotherapy).
Clinical trial evidence shows that, compared with placebo, olaparib after neoadjuvant or...
This evaluation uses new cost-effectiveness estimates to update olaparib for previously treated BRCA mutation-positive hormone-relapsed metastatic prostate cancer (NICE technology appraisal guidance TA831). No new clinical evidence was reviewed. Treatments for BRCA mutation-positive hormone-relapsed meta...
Evidence-based recommendations on olaparib (Lynparza) for previously treated BRCA mutation-positive hormone-relapsed metastatic prostate cancer in adults.
Commercial arrangement
There is a simple discount patient access scheme for olaparib. NHS organisations can get details on the Commercial Access and ...
Early value assessment (EVA) guidance on point-of-care tests for urinary tract infections to improve antimicrobial prescribing.
Guidance development process
Early value assessment (EVA) guidance rapidly provides recommendations on promising health technologies that have the potential to address national...
Evidence-based recommendations on ripretinib (Qinlock) for treating gastrointestinal stromal tumour in adults after 3 or more treatments....
Evidence-based recommendations on voclosporin (Lupkynis) with mycophenolate mofetil for treating lupus nephritis in adults....
Evidence-based recommendations on pembrolizumab (Keytruda) plus chemotherapy with or without bevacizumab for persistent, recurrent or metastatic cervical cancer in adults....
