elaborar una propuesta estratégica para el abordaje integral de esta enfermedad, delegando la
coordinación del componente de Investigación en la Unidad de Investigaciones SALUD del Instituto Nacional de Salud
The purpose of this essay is to examine CKDus
case defi nition(s), epidemiology and causal hypotheses in reports
of CKDu epidemics in agricultural communities globally.
Characterize clinical manifestations (including extrarenal) and pathophysiology of chronic kidney disease of nontraditional causes in Salvadoran farming communities.
To evaluate the geographic relationship between unspecified chronic kidney disease (unCKD) and nondiabetic chronic renal failure (ndESRD) hospital admissions in El Salvador with the proximity to cultivated crops and ambient temperatures.
Characterize histopathology of chronic kidney disease of unknown etiology in patients from Salvadoran agricultural communities, describe renal damage associated with each disease stage, and assess associations between histopathological alterations and sociodemographic variables.
Determine prevalence of CKD, CKD risk factors (traditional and nontraditional) and renal damage markers in the adult population of specific rural areas in El Salvador; measure population distribution of renal function; and identify associated risk factors in CKD patients detected.