The term autism describes qualitative differences and impairments in reciprocal social interaction
and social communication, combined with restricted interests and rigid and repetitive behaviours,
often with a lifelong impact. In addition to these features, autistic children and young people
frequently e...
Fraenkel, Liana;
Bathon, Joan;
England, Bryant;
St Clair, William;
Arayssi, Thurayya;
Carandang, Kristine;
Deane, Kevin;
Genovese, Mark;
Huston, Kent;
Kerr, Gail;
Akl, Elie;
Turner, Amy.
To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluat...
The previous treatment guide for type 2 diabetes was prepared by the Estonian Society of Endocrinology
led in 2016 and discussed type 2 diabetes screening, diagnosis and
pharmacological treatment (1). The guideline was prepared as an expert opinion/consensus and no
followed the agreed methodology, which ...
Patients with primary brain tumours often develop vasogenic edema and increased intracranial
pressure. Corticosteroid therapy improves this in most patients, generally within 48 hours. As such, corticosteroid therapy is sometimes a necessary prerequisite to embarking on chemotherapy
and radiotherapy foll...
Worldwide, people acquire more than 1 million curable sexually transmitted infections (STIs) every day. Based on prevalence data from 2009 to 2016, in 2019, WHO published estimates of new cases of chlamydia, gonorrhoea, syphilis and trichomoniasis, showing total estimated incident cases of 376.4 million ...
The incidence and prevalence of Crohn's disease (CD) is rising globally. Patients with moderate to severe CD are at high risk for needing surgery and hospitalization and for developing disease-related complications, corticosteroid dependence, and serious infections. Optimal management of outpatients with...
Before initiation of antibiotic treatment, a specimen should be obtained for microbiological diagnostics. The first choice is an ulcer biopsy, as this method has the best microbiological diagnostic precision. It is important that the clinician arrives at the choice of diagnostics in consultation with the...
Professional observers are independent persons who have in-depth knowledge of both children’s normal behaviour and
development and of ADHD, and who take a multidisciplinary approach to ADHD in their daily work. The observation
must be geared to the specific problem with the child in question...
A clinical summary of this KDP was published in the Journal of the Ministry of Health of the Czech Republic .
Diabetes mellitus is a heterogeneous group of diseases whose uniform laboratory manifestation is hyperglycemia. In 2017, the number of diabetics in the Czech Republic was 995,613, of which 762,...
This guideline covers advice on the diagnosis and management of tension-type headache, migraine (including migraine with aura and menstrual-related migraine), cluster headache and medication overuse headache in young people (aged 12 years and older) and adults. It aims to improve the recognition and mana...
