The incidence and prevalence of Crohn's disease (CD) is rising globally. Patients with moderate to severe CD are at high risk for needing surgery and hospitalization and for developing disease-related complications, corticosteroid dependence, and serious infections. Optimal management of outpatients with...
Before initiation of antibiotic treatment, a specimen should be obtained for microbiological diagnostics. The first choice is an ulcer biopsy, as this method has the best microbiological diagnostic precision. It is important that the clinician arrives at the choice of diagnostics in consultation with the...
Professional observers are independent persons who have in-depth knowledge of both children’s normal behaviour and
development and of ADHD, and who take a multidisciplinary approach to ADHD in their daily work. The observation
must be geared to the specific problem with the child in question...
A clinical summary of this KDP was published in the Journal of the Ministry of Health of the Czech Republic .
Diabetes mellitus is a heterogeneous group of diseases whose uniform laboratory manifestation is hyperglycemia. In 2017, the number of diabetics in the Czech Republic was 995,613, of which 762,...
This guideline covers advice on the diagnosis and management of tension-type headache, migraine (including migraine with aura and menstrual-related migraine), cluster headache and medication overuse headache in young people (aged 12 years and older) and adults. It aims to improve the recognition and mana...
The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care. It offers best practice advice on managing epilepsy to improve health outcomes so that people with epilepsy can fully participate in daily life.
MHRA advice o...
Clinical question What are the benefits and harms of sodium-glucose cotransporter 2 (SGLT-2) inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists when added to usual care (lifestyle interventions and/or other diabetes drugs) in adults with type 2 diabetes at different risk for cardiovascular ...
Esta guía de práctica clínica, en cuya elaboración se siguió el método GRADE, tiene por objeto proveer recomendaciones para el manejo de pacientes adultos críticos con COVID-19 atendidos en las unidades de cuidados intensivos. Ofrece recomendaciones basadas en evidencia para la identificación de ...
Gestion des soins aux patients,
Soins de réanimation,
COVID-19/imagerie diagnostique,
COVID-19/complications,
COVID-19/traitement médicamenteux,
SARS-CoV-2/effets des médicaments et des substances chimiques,
Antirétroviraux/usage thérapeutique,
Amériques/épidémiologie,
Facteurs de risque,
Respirateurs artificiels,
Plasma sanguin/immunologie,
Antibactériens/usage thérapeutique,
Facteurs immunologiques/usage thérapeutique
Miravitlles, Marc;
Calle, Myriam;
Molina, Jesús;
Almagro, Pere;
Gómez, José-Tomás;
Trigueros, Juan Antonio;
Cosío, Borja G;
Casanova, Ciro;
López-Camposb, José Luis;
Riescob, Juan Antonio;
Simonetl, Pere;
Rigau, David;
Soriano, Joan B;
Ancochea, Julio;
Soler-Cataluña, Juan José.
The Spanish COPD Guidelines (GesEPOC) were first published in 2012, and since then have undergone a series of updates incorporating new evidence on the diagnosis and treatment of COPD. GesEPOC was drawn up in partnership with scientific societies involved in the treatment of COPD and the Spanish Patients...
Training/instruction of staff in using the selected psychometric test is recommended to achieve sufficiently high
sensibility and specificity. As delirium is a fluctuating condition, repeated testing after hours or days is recommended,
as well as in connection with mental changes in patients with one or ...
