The term autism describes qualitative differences and impairments in reciprocal social interaction
and social communication, combined with restricted interests and rigid and repetitive behaviours,
often with a lifelong impact. In addition to these features, autistic children and young people
frequently e...
Fraenkel, Liana;
Bathon, Joan;
England, Bryant;
St Clair, William;
Arayssi, Thurayya;
Carandang, Kristine;
Deane, Kevin;
Genovese, Mark;
Huston, Kent;
Kerr, Gail;
Akl, Elie;
Turner, Amy.
To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluat...
The previous treatment guide for type 2 diabetes was prepared by the Estonian Society of Endocrinology
led in 2016 and discussed type 2 diabetes screening, diagnosis and
pharmacological treatment (1). The guideline was prepared as an expert opinion/consensus and no
followed the agreed methodology, which ...
Patients with primary brain tumours often develop vasogenic edema and increased intracranial
pressure. Corticosteroid therapy improves this in most patients, generally within 48 hours. As such, corticosteroid therapy is sometimes a necessary prerequisite to embarking on chemotherapy
and radiotherapy foll...
Worldwide, people acquire more than 1 million curable sexually transmitted infections (STIs) every day. Based on prevalence data from 2009 to 2016, in 2019, WHO published estimates of new cases of chlamydia, gonorrhoea, syphilis and trichomoniasis, showing total estimated incident cases of 376.4 million ...
The incidence and prevalence of Crohn's disease (CD) is rising globally. Patients with moderate to severe CD are at high risk for needing surgery and hospitalization and for developing disease-related complications, corticosteroid dependence, and serious infections. Optimal management of outpatients with...
To describe evidence-based practice for managing the labour, delivery, and postpartum care of people with physical disabilities in Canada. This guideline addresses the needs of people with physical disabilities, with a focus on conditions that affect strength and mobility, as well as those that affect ne...
To provide an evidence-based algorithm to guide the diagnosis and management of pregnancy of unknown location and tubal and nontubal ectopic pregnancy. All patients of reproductive age. The implementation of this guideline aims to benefit patients with positive β-human chorionic gonadotropin results and...
To provide an update on current recommendations for cytomegalovirus (CMV) infection during pregnancy. The objectives of this guideline are: To improve perinatal care providers’ awareness of the consequences of maternal CMV infection for the fetus and the infant; To emphasize the importance of educating...
Paterson, Ian;
White, James;
Butler, Craig;
Connelly, Kim;
Guerra, Peter;
Hill, Michael;
Sarak, Bradley;
Sterns, Laurence;
Verma, Atul;
Wan, Douglas;
Crean, Andrew;
Grosse-Wortmann, Lars;
Hanneman, Kate;
Leipsic, Jonathon;
Manlucu, Jaimie;
Villemaire, Christine;
Wald, Rachel;
Windram, Jonathan.
Magnetic resonance imaging (MRI) is often considered the gold-standard test for characterizing cardiac as well as noncardiac structure and function. However, many patients with cardiac implantable electronic devices (CIEDs) and/or severe renal dysfunction are unable to undergo this test because of safety...
