El cáncer de próstata metastásico se presenta en el 20% de pacientes al momento del
diagnóstico de cáncer de próstata (1). Los sitios comunes de diseminación metastásica
locorregional son los ganglios linfáticos (99%) y huesos como pelvis, cadera y esqueleto axial
(84%); mientras que las localiz...
Esta guía de práctica clínica contiene recomendaciones sobre el manejo de pacientes con COVID-19 leve (no presentan ninguno de los criterios de severidad propuestos por la OMS) de comienzo reciente (menos de 7 días desde el inicio de los síntomas). Aborda intervenciones priorizadas por el Ministerio...
Nadee, Sarah;
Pervez, Alina;
Abid, Muhammad Abbas;
Rizvi, Nashia Ali;
Ayub, Bushra;
Ahmed, Sibtain;
Jafri, Lena;
Habib Khan, Asyha;
Haider, Adil H;
Sheikh, Aisha;
Khalid, Rehab Naeem;
Aamdani, Salima Saleem;
Mustafa, Mohsin Ali;
Riaz, Mehmood;
Irfan, Khadija;
Noordin, Shahryar;
Majid, Hafsa;
Umer, Masood;
Zehra, Nawazish.
Due to its high prevalence, we aimed to create postmenopausal osteoporosis clinical practice guideline via GRADE-ADOLOPMENT for Pakistan. We recommend a higher dose (2000-4000 IU) of vitamin D for osteoporotic patients who are old, have malabsorption, or are obese. The guideline will help standardize car...
This guideline covers assessment and early management of head injury in babies, children, young people and adults. It aims to ensure that people have the right care for the severity of their head injury, including direct referral to specialist care if needed....
Evidence-based recommendations on risankizumab (Skyrizi) for previously treated moderately to severely active Crohn's disease in people 16 years and over....
NICE is unable to make a recommendation on ciltacabtagene autoleucel (Carvykti) for treating relapsed or refractory multiple myeloma in adults. This is because Janssen withdrew its evidence submission for the appraisal. We will review this decision if the company decides to make a submission....
Evidence-based recommendations on difelikefalin (Kapruvia) for pruritus in adults with chronic kidney disease having haemodialysis....
Six digitally enabled therapies can be used as treatment options for
adults with anxiety disorders while further evidence is generated on their
clinical and cost effectiveness, once they have appropriate approval.
The following technologies can only be used once they have Digital
Technology Assessment Cr...
Three digitally enabled therapies can be used as treatment options for
adults with depression while further evidence is generated on their
clinical and cost effectiveness. The therapies should be used with
support from a trained practitioner or therapist in NHS Talking Therapies
for anxiety and depressio...
Athanazio, Rodrigo Abensur;
Tanni, Suzana Erico;
Ferreira, Juliana;
Fuccio, Marcelo de;
Marostica, Paulo José Cauduro;
Ferreira, Juliana;
Dalcin, Paulo de Tarso Roth;
Esposito, Concetta;
Canan, Mariane Gonçalves Martynychen;
Coelho, Liana Sousa;
Firmida, Mônica de Cássia;
Almeida, Marina Buarque de;
Monte, Luciana de Freitas Velloso;
Souza, Edna Lúcia;
Pinto, Leonardo Araujo;
Rached, Samia Zahi;
Oliveira, Verônica Stasiak Bednarczuk de;
Riedi, Carlos Antonio;
Silva Filho, Luiz Vicente Ribeiro Ferreira da.
A fibrose cística (FC) é uma doença genética que resulta em disfunção da proteína
reguladora de condutância transmembrana da FC (CFTR), que é um canal de cloro e
bicarbonato expresso na porção apical de células epiteliais de diversos órgãos. A
disfunção dessa proteína resulta em manifest...
