The purpose of this report is to inform deliberations among policymakers and stakeholders. It summarises the best available evidence regarding the design and implementation of policies for extending the use of non-medically trained primary health care workers to deliver cost-effective maternal and child health interventions. This policy brief brings together global research evidence (from systematic reviews) and local evidence to inform deliberations about optimising the use of different cadre of health workers to deliver cost-effective maternal and child health services.