This document provides a standard-based tool for health workforce planners and decision-makers developing an electronic system or modifying an existing health information system to count and document all health workers within national and subnational contexts. The minimum data set for health workforce registry provided in this document can be used by ministries of health to support the development of standardized health workforce information systems. The minimum data set allows standardization of data values within existing electronic human resources for health (HRH) information systems. When used appropriately by information systems designers and software developers, a functional electronic health workforce registry can be designed to enable health workforce data interoperability—i.e. the ability to exchange health workforce data between software applications and computer systems within broader sub-national or national health information systems. Through this approach, rapid aggregation and display of health workforce data for decision-making can be fully realized.