This quick guide contains the key recommendations from the national clinical guideline for the treatment of brain metastases. The national clinical guideline for the treatment of brain metastases focuses on treatment, including clarification of the treatment modality to be used in each individual case. Brain metastases are a heterogeneous disorder for which the choice of treatment depends on the prognosis group as well as several tumour biological factors. The guideline generally does not differentiate between metastases from different primary tumours. For each focused question, it is specified how the population was delimited for each individual literature search.