WHO recommendations: policy of interventionist versus expectant management of severe pre-eclampsia before term
Ano de publicação: 2018
The Department of Reproductive Health and Research of the World Health Organization
gratefully acknowledges the contributions of many individuals and organizations to
the updating of these recommendations. Work on this update was coordinated by
Olufemi Oladapo, Joshua Vogel and A. Metin Gülmezoglu of the WHO Department of
Reproductive Health and Research.
WHO extends its sincere thanks to Edgardo Abalos, Ebun Adejuyigbe, Shabina Ariff,
Jemima Dennis-Antwi, Luz Maria De-Regil, Christine East, Lynn Freedman, Pisake
Lumbiganon, Anita Maepioh, James Neilson, Hiromi Obara, Rachel Plachcinski, Zahida
Qureshi, Kathleen Rasmussen, Niveen Abu Rmeileh and Eleni Tsigas who served as
members of the Guideline Development Group (GDG), and to Zahida Qureshi (Chair)
and Jim Neilson (Vice-Chair) for chairing the meeting. We also thank José Guilherme
Cecatti, Sylvia Deganus, M Jeeva Sankar, Hayfaa Wahabi, Jack Moodley, Jane Sandall,
Ola Shaker and Nguyen Xuan Hoi who were members of the External Review Group.
WHO also gratefully acknowledges the contribution of the members of the Executive
Guideline Steering Group.
Anna Cuthbert, Leanne Jones, Frances Kellie and Myfanwy Williams reviewed
the scientific evidence, prepared the Grading of Recommendations, Assessment,
Development, and Evaluation (GRADE) tables and drafted the narrative summary of
evidence. Joshua Vogel and Olufemi Oladapo revised the narrative summaries and
double-checked the corresponding GRADE tables and prepared the Evidence-toDecision frameworks. Joshua Vogel, Olufemi Oladapo, A. Metin Gülmezoglu, Ana Pilar
Betran, Özge Tuncalp and Mercedes Bonet commented on the draft document before
it was reviewed by participants at the WHO Guideline Development Group meeting. The
External Review Group peer reviewed the final document.
We acknowledge the various organizations that were represented by observers,
including Deborah Armbruster and Mary-Ellen Stanton (United States Agency for
International Development), Kathleen Hill (Maternal and Child Survival Program/
Jhpiego), Jerker Liljestrand (Bill & Melinda Gates Foundation), Lesley Page (International
Confederation of Midwives), Gerard Visser (International Federation of Gynaecology and
Obstetrics) and Charlotte Warren (Ending Eclampsia Project, Population Council). We
appreciate the contributions of WHO Regional Office staff – Nino Berdzuli, Bremen De
Mucio, Chandani Anoma Jayathilaka, Ramez Khairi Mahaini, Léopold Ouedraogo and
Howard Sobel.
The United States Agency for International Development and the Department of
Reproductive Health and Research provided financial support for this work. The views
of the funding bodies have not influenced the content of these recommendations.