The WHO Therapeutics and COVID-19: living guideline contains the Organization’s most up-to-date recommendations for the use of therapeutics in the treatment of COVID-19. The latest version of this living guideline is available in pdf format (via the ‘Download’ button) and via an online platform, an...
Inibidores de Janus Quinases/uso terapêutico,
COVID-19/tratamento farmacológico,
Antivirais/uso terapêutico,
Ivermectina/uso terapêutico,
Hidroxicloroquina/uso terapêutico,
Plasma/imunologia,
Fluvoxamina/uso terapêutico,
Colchicina/uso terapêutico,
Imunização Passiva,
Receptores de Interleucina-6/uso terapêutico,
Lopinavir/uso terapêutico,
Corticosteroides/uso terapêutico
Falavigna, Maicon;
Stein, Cinara;
Amaral, José Luiz Gomes do;
Azevedo, Luciano Cesar Pontes de;
Belli, Karlyse Claudino;
Colpani, Verônica;
Cunha, Clóvis Arns da;
Dal-Pizzol, Felipe;
Dias, Maria Beatriz Souza;
Ferreira, Juliana Carvalho;
Freitas, Ana Paula da Rocha;
Gräf, Débora Dalmas;
Guimarães, Hélio Penna;
Lobo, Suzana Margareth Ajeje;
Monteiro, José Tadeu;
Nunes, Michelle Silva;
Oliveira, Maura Salaroli de;
Prado, Clementina Corah Lucas;
Santos, Vania Cristina Canuto;
Silva, Rosemeri Maurici da;
Sobreira, Marcone Lima;
Veiga, Viviane Cordeiro;
Vidal, Ávila Teixeira;
Xavier, Ricardo Machado;
Zavascki, Alexandre Prehn;
Machado, Flávia Ribeiro;
Carvalho, Carlos Roberto Ribeiro de.
Há diversas terapias sendo utilizadas ou propostas para a COVID-19, muitas carecendo de apropriada avaliação de efetividade e segurança. O propósito deste documento é elaborar recomendações para subsidiar decisões sobre o tratamento farmacológico de pacientes hospitalizados com COVID-19 no Bras...
Rochwerg, Bram;
Agoritsas, Thomas;
Lamontagne, François;
Leo, Yee-Sin;
Macdonald, Helen;
Agarwal, Arnav;
Zeng, Linan;
Lytvyn, Lyubov;
Appiah, John Adabie;
Amin, Wagdy;
Arabi, Yaseen;
Blumberg, Lucille;
Burhan, Erlina;
Bausch, Frederique;
Calfee, Carolyn S;
Cao, Bin;
Cecconi, Maurizio;
Chanda, Duncan;
Cooke, Graham;
Du, Bin;
Dunning, Jake;
Geduld, Heike;
Gee, Patrick;
Hashimi, Madiha;
Hui, David S;
Kabra, Sushil;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kim, Yae-Jean;
Kissoon, Niranjan;
Kwizera, Arthur;
Laake, Jon Henrik;
Machado, Flavia R;
Mahaka, Imelda;
Manai, Hela;
Mino, Greta;
Nsutebu, Emmanuel;
Pshenichnaya, Natalia;
Qadir, Nida;
Sabzwari, Saniya;
Sarin, Rohit;
Sharland, Michael;
Shen, Yinzhong;
Ranganathan, Shalini Sri;
Souza, Joao;
Ugarte, Sebastian;
Venkatapuram, Sridhar;
Dat, Vu Quoc;
Vuyiseka, Dubula;
Wijewickrama, Ananda;
Maguire, Brittany;
Zeraatkar, Dena;
Bartoszko, Jessica;
Ge, Long;
Brignardello-Petersen, Romina;
Siemieniuk, Reed;
Guyatt, Gordon;
Diaz, Janet;
Jacobs, Michael;
Vandvik, Per Olav.
What is the role of drug interventions in the treatment of patients with covid-19? The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint publication of results from the WHO SOLIDARITY trial. It contains a weak or conditional recommendation against th...
Jin, Ying-Hui;
Zhan, Qing-Yuan;
Peng, Zhi-Yong;
Ren, Xue-Qun;
Yin, Xun-Tao;
Cai, Lin;
Yuan, Yu-Feng;
Yue, Ji-Rong;
Zhang, Xiao-Chun;
Yang, Qi-Wen;
Ji, Jianguang;
Xia, Jian;
Li, Yi-Rong;
Zhou, Fu-Xiang;
Gao, Ya-Dong;
Yu, Zhui;
Xu, Feng;
Tu, Ming-Li;
Tan, Li-Ming;
Yang, Min;
Chen, Fang;
Zhang, Xiao-Ju;
Zeng, Mei;
Zhu, Yu;
Liu, Xin-Can;
Yang, Jian;
Zhao, Dong-Chi;
Ding, Yu-Feng;
Hou, Ning;
Wang, Fu-Bing;
Chen, Hao;
Zhang, Yong-Gang;
Li, Wei;
Chen, Wen;
Shi, Yue-Xian;
Yang, Xiu-Zhi;
Wang, Xue-Jun;
Zhong, Yan-Jun;
Zhao, Ming-Juan;
Li, Bing-Hui;
Ma, Lin-Lu;
Zi, Hao;
Wang, Na;
Wang, Yun-Yun;
Yu, Shao-Fu;
Li, Lu-Yao;
Huang, Qiao;
Weng, Hong;
Ren, Xiang-Ying;
Luo, Li-Sha;
Fan, Man-Ru;
Huang, Di;
Xue, Hong-Yang;
Yu, Lin-Xin;
Gao, Jin-Ping;
Deng, Tong;
Zeng, Xian-Tao;
Li, Hong-Jun;
Cheng, Zhen-Shun;
Yao, Xiaomei;
Wang, Xing-Huan.
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness,
coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis
and treatment guidelines for clinicians caring for patients are needed. In the ...
Quimioprevenção/métodos,
Infecções por Coronavirus/diagnóstico,
Infecções por Coronavirus/tratamento farmacológico,
Pneumonia Viral/diagnóstico,
Pneumonia Viral/tratamento farmacológico,
Pandemias/prevenção & controle,
Betacoronavirus/efeitos dos fármacos,
Prática Clínica Baseada em Evidências/métodos,
Antirretrovirais/uso terapêutico,
Lopinavir/uso terapêutico,
Cloroquina/uso terapêutico,
Receptores de Interleucina-6/uso terapêutico,
Hidroxicloroquina/uso terapêutico,
Plasma/imunologia
Falavigna, Maicon;
Colpani, Verônica;
Stein, Cinara;
Azevedo, Luciano César Pontes;
Bagattini, Ângela Maria;
Brito, Gabriela Vilela de;
Chatkin, José Miguel;
Cimerman, Sérgio;
Corradi, Mirian de Freitas Dal Ben;
Cunha, Clóvis Arns da;
Medeiros, Flávia Cordeiro de;
Oliveira Júnior, Haliton Alves de;
Fritscher , Leandro Genehr;
Gazzana, Marcelo Basso;
Graf, Débora Dalmas;
Marra, Lays Pires;
Matuoka , Jéssica Yumi;
Nunes, Michelle Silva;
Pachito, Daniela Vianna;
Pagano, Cássia Garcia Moraes;
Parreira, Patrícia do Carmo Silva;
Riera, Rachel;
Silva Júnior, Amilton;
Tavares, Bruno de Melo;
Zavascki, Alexandre Prehn;
Rosa, Régis Goulart;
Dal-Pizzol, Felipe.
Different therapies are currently used, considered, or proposed for the treatment of COVID-19; for many of those therapies, no appropriate assessment of effectiveness and safety was performed. This document aims to provide scientifically available evidence-based information in a transparent interpretatio...
Infecções por Coronavirus/tratamento farmacológico,
Aminoquinolinas/uso terapêutico,
Oseltamivir/uso terapêutico,
Lopinavir/uso terapêutico,
Ritonavir/uso terapêutico,
Corticosteroides/uso terapêutico,
Heparina/uso terapêutico,
Antibacterianos/uso terapêutico,
Betacoronavirus/efeitos dos fármacos,
Pneumonia Viral/tratamento farmacológico,
Pandemias/prevenção & controle
China has managed to control the coronavirus disease (COVID-19) with confinement measurements and treatment strategies, while other countries are struggling to contain the spread. This study discussesthe guidelines related to COVID-19 in China in order to provide important references for other countries
...
Betacoronavirus/efeitos dos fármacos,
Pneumonia Viral/epidemiologia,
Infecções por Coronavirus/epidemiologia,
China/epidemiologia,
Pandemias/prevenção & controle,
Pandemias/estatística & dados numéricos,
Monitoramento Epidemiológico,
Gestão da Informação em Saúde/métodos,
Interferons/uso terapêutico,
Lopinavir/uso terapêutico,
Ritonavir/uso terapêutico,
Ribavirina/uso terapêutico,
Cloroquina/uso terapêutico,
Infecções por Coronavirus/tratamento farmacológico,
Pneumonia Viral/tratamento farmacológico
Bhimraj, Adarsh;
Morgan, Rebecca L;
Shumaker, Amy Hirsch;
Lavergne, Valery;
Baden, Lindsey;
Cheng, Vincent Chi-Chung;
Edwards, Kathryn M;
Gandhi, Rajesh;
Muller, William J;
O’Horo, John C;
Shoham, Shmuel;
Murad, M. Hassan;
Mustafa, Reem A;
Sultan, Shahnaz;
Falck-Ytter, Yngve.
Develop evidence-based rapid guidelines intended to support patients, clinicians and other health-care professionals in their decisions about treatment and management of patients with COVID-19....