A clinical summary of this KDP was published in the Journal of the Ministry of Health of the Czech Republic .
Ischemic cerebrovascular events (iCMP) make up 88% of all CMPs, in the Czech Republic the incidence of iCMP is currently 211 cases per 100,000 inhabitants per year and the prevalence is estimat...
Miller, R. E;
Leary, A;
Scott, C. L;
Serra, V;
Lord , C. J;
Bowtell, D;
Chang, D. K;
Garsed, D. W;
Jonkers, J;
Ledermann, J. A;
Nik-Zainal, S;
Ray-Coquard, I;
Shah, S. P;
Matias-Guiu, X;
Swisher, E. M;
Yates, L. R.
The European Society for Medical Oncology (ESMO) Translational Research and Precision Medicine Working Group identified that there is currently uncertainty within the oncology community surrounding the different methods for HRD testing in HGSC. To address this, a collaborative project was launched with a...
This guideline covers managing neuropathic pain (nerve pain) with pharmacological treatments (drugs) in adults in non-specialist settings. It aims to improve quality of life for people with conditions such as neuralgia, shingles and diabetic neuropathy by reducing pain and promoting increased participati...
O'Malley, Patrick G;
Arnold, Michael J;
Pharm, Cathy Kelley;
Spacek, Lance;
Buelt, Andrew;
Natarajan, Sundar;
Donahue, Mark P;
Vagichev, Elena;
Ballard-Hernandez, Jennifer;
Logan, Amanda;
Thomas, Lauren;
Ritter, Joan;
Neubauer, Brian E;
Downs, John R.
In June 2020, the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) released a joint update of their clinical practice guideline for managing dyslipidemia to reduce cardiovascular disease risk in adults. This synopsis describes the major recommendations. The guideline panel de...
The update of the treatment guide "Management of adult asthma in primary care" was initiated because five years had passed since the publication of the original guide. The procedure for updating treatment manuals is written in the "Estonian manual for the preparation of treatment manuals" (2020). At the ...
This guideline covers care for adults (aged 18 and over) having elective or emergency surgery, including dental surgery. It covers all phases of perioperative care, from the time people are booked for surgery until they are discharged afterward. The guideline includes recommendations on preparing for sur...
Timsit, Jean-François;
Baleine, Julien;
Bernard, Louis;
Calvino-Gunther, Silvia;
Darmon, Michael;
Dellamonica, Jean;
Desruennes, Eric;
Leone, Marc;
Lepape, Alain;
Leroy, Olivier;
Lucet, Jean-Christophe;
Merchaoui, Zied;
Mimoz, Olivier;
Misset, Benoit;
Parienti, Jean-Jacques;
Quenot, Jean-Pierre;
Roch, Antoine;
Schmidt, Matthieu;
Slama, Michel;
Souweine, Bertrand;
Zahar, Jean-Ralph;
Zingg, Walter;
Bodet-Contentin, Laetitia;
Maxime, Virginie.
The French Society of Intensive Care Medicine (SRLF), jointly with the French-Speaking Group of Paediatric Emer‑
gency Rooms and Intensive Care Units (GFRUP) and the French-Speaking Association of Paediatric Surgical Inten‑
sivists (ADARPEF), worked out guidelines for the management of central venous...
Rochwerg, Bram;
Agoritsas, Thomas;
Lamontagne, François;
Leo, Yee-Sin;
Macdonald, Helen;
Agarwal, Arnav;
Zeng, Linan;
Lytvyn, Lyubov;
Appiah, John Adabie;
Amin, Wagdy;
Arabi, Yaseen;
Blumberg, Lucille;
Burhan, Erlina;
Bausch, Frederique;
Calfee, Carolyn S;
Cao, Bin;
Cecconi, Maurizio;
Chanda, Duncan;
Cooke, Graham;
Du, Bin;
Dunning, Jake;
Geduld, Heike;
Gee, Patrick;
Hashimi, Madiha;
Hui, David S;
Kabra, Sushil;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kim, Yae-Jean;
Kissoon, Niranjan;
Kwizera, Arthur;
Laake, Jon Henrik;
Machado, Flavia R;
Mahaka, Imelda;
Manai, Hela;
Mino, Greta;
Nsutebu, Emmanuel;
Pshenichnaya, Natalia;
Qadir, Nida;
Sabzwari, Saniya;
Sarin, Rohit;
Sharland, Michael;
Shen, Yinzhong;
Ranganathan, Shalini Sri;
Souza, Joao;
Ugarte, Sebastian;
Venkatapuram, Sridhar;
Dat, Vu Quoc;
Vuyiseka, Dubula;
Wijewickrama, Ananda;
Maguire, Brittany;
Zeraatkar, Dena;
Bartoszko, Jessica;
Ge, Long;
Brignardello-Petersen, Romina;
Siemieniuk, Reed;
Guyatt, Gordon;
Diaz, Janet;
Jacobs, Michael;
Vandvik, Per Olav.
What is the role of drug interventions in the treatment of patients with covid-19? The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint publication of results from the WHO SOLIDARITY trial. It contains a weak or conditional recommendation against th...
Jin, Ying-Hui;
Zhan, Qing-Yuan;
Peng, Zhi-Yong;
Ren, Xue-Qun;
Yin, Xun-Tao;
Cai, Lin;
Yuan, Yu-Feng;
Yue, Ji-Rong;
Zhang, Xiao-Chun;
Yang, Qi-Wen;
Ji, Jianguang;
Xia, Jian;
Li, Yi-Rong;
Zhou, Fu-Xiang;
Gao, Ya-Dong;
Yu, Zhui;
Xu, Feng;
Tu, Ming-Li;
Tan, Li-Ming;
Yang, Min;
Chen, Fang;
Zhang, Xiao-Ju;
Zeng, Mei;
Zhu, Yu;
Liu, Xin-Can;
Yang, Jian;
Zhao, Dong-Chi;
Ding, Yu-Feng;
Hou, Ning;
Wang, Fu-Bing;
Chen, Hao;
Zhang, Yong-Gang;
Li, Wei;
Chen, Wen;
Shi, Yue-Xian;
Yang, Xiu-Zhi;
Wang, Xue-Jun;
Zhong, Yan-Jun;
Zhao, Ming-Juan;
Li, Bing-Hui;
Ma, Lin-Lu;
Zi, Hao;
Wang, Na;
Wang, Yun-Yun;
Yu, Shao-Fu;
Li, Lu-Yao;
Huang, Qiao;
Weng, Hong;
Ren, Xiang-Ying;
Luo, Li-Sha;
Fan, Man-Ru;
Huang, Di;
Xue, Hong-Yang;
Yu, Lin-Xin;
Gao, Jin-Ping;
Deng, Tong;
Zeng, Xian-Tao;
Li, Hong-Jun;
Cheng, Zhen-Shun;
Yao, Xiaomei;
Wang, Xing-Huan.
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness,
coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis
and treatment guidelines for clinicians caring for patients are needed. In the ...
Quimioprevenção/métodos,
Infecções por Coronavirus/diagnóstico,
Infecções por Coronavirus/tratamento farmacológico,
Pneumonia Viral/diagnóstico,
Pneumonia Viral/tratamento farmacológico,
Pandemias/prevenção & controle,
Betacoronavirus/efeitos dos fármacos,
Prática Clínica Baseada em Evidências/métodos,
Antirretrovirais/uso terapêutico,
Lopinavir/uso terapêutico,
Cloroquina/uso terapêutico,
Receptores de Interleucina-6/uso terapêutico,
Hidroxicloroquina/uso terapêutico,
Plasma/imunologia
Rochwerg, Bram;
Agarwal, Arnav;
Zeng, Linan;
Leo, Yee-Sin;
Appiah, John Adabie;
Agoritsas, Thomas;
Bartoszko, Jessica;
Brignardello-Petersen, Romina;
Ergan, Begum;
Ge, Long;
Geduld, Heike;
Gershengorn, Hayley B;
Manai, Hela;
Huang, Minhua;
Lamontagne, François;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kurian, Linda;
Kwizera, Arthur;
Murthy, Srinivas;
Qadir, Nida;
Siemieniuk, Reed;
Silvestre, Maria Asuncion;
Vandvik, Per Olav;
Ye, Zhikang;
Zeraatkar, Dena;
Guyatt, Gordon.
Clinical question: What is the role of remdesivir in the treatment of severe covid-19? This guideline was triggered by the ACTT-1 trial published in the New England Journal of Medicine on 22 May 2020.Remdesivir has received worldwide attention as a potentially effective treatment for severe covid-19. Aft...
