Total: 2266

    Summary for patients: pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults

    Ann. intern. med; 176 (2), 2023
    Osteoporosis is a disease, common in older age, that makes your bones weaker and can lead to a fracture. People with previous fractures and those who have other risk factors for fractures, including family history of fractures, vitamin D deficiency or low calcium intake, smoking, excessive alcohol intake...

    Management of adult renal trauma: a practice management guideline from the eastern association for the surgery of trauma

    BMC surg. (Online); 23 (22), 2023
    The kidney is the most frequently injured component of the genitourinary system, accounting for 5% of all trauma cases. Several guidelines by different societies address the management of urological trauma. However, unanswered questions remain regarding optimal use of angioembolization in hemodynamically...

    Maribavir for treating refractory cytomegalovirus infection after transplant

    Evidence-based recommendations on maribavir (Livtencity) for cytomegalovirus infection in adults after transplant. Commercial arrangement There is a simple discount patient access scheme for maribavir. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisat...

    Trabeculectomy with a biodegradable collagen matrix implant for glaucoma

    Evidence-based recommendations on trabeculectomy with a biodegradable collagen matrix implant for glaucoma. This involves cutting a small flap in the white of the eye and putting a patch over the flap to help healing and prevent scarring. Fluid slowly drains out of the flap and the patch dissolves over t...

    Angiotensin II for treating vasosuppressor-resistant hypotension caused by septic or distributive shock (terminated appraisal)

    NICE is unable to make a recommendation on angiotensin II for treating vasosuppressor-resistant hypotension caused by septic or distributive shock. This is because Paion AG did not provide an evidence submission. We will review this decision if the company decides to make a submission....

    MRI-based technologies for assessing non-alcoholic fatty liver disease

    This guidance replaces the NICE medtech innovation briefing on LiverMultiScan for liver disease (MIB181). Your responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expecte...

    Lenvatinib with pembrolizumab for untreated advanced renal cell carcinoma

    Evidence-based recommendations on lenvatinib (Kisplyx) with pembrolizumab (Keytruda) for untreated advanced renal cell carcinoma in adults. Commercial arrangements There is a simple discount patient access scheme for lenvatinib and a commercial access agreement for pembrolizumab. NHS organisations can g...

    Laparoscopic insertion of a magnetic ring for gastro-oesophageal reflux disease

    Evidence-based recommendations on laparoscopic insertion of a magnetic ring for gastro-oesophageal reflux disease. This involves placing a ring of beads outside of the food pipe, just above the stomach. Magnets inside the beads hold them together to keep the food pipe closed but are weak enough to move a...

    Nivolumab with platinum- and fluoropyrimidine-based chemotherapy for untreated HER2-negative advanced gastric, gastro-oesophageal junction or oesophageal adenocarcinoma

    Next Evidence-based recommendations on nivolumab (Opdivo) with platinum- and fluoropyrimidine-based chemotherapy for untreated HER2-negative advanced gastric, gastro-oesophageal junction or oesophageal adenocarcinoma in adults. Commercial arrangement There is a commercial access agreement for nivolumab...

    Transcutaneous electrical stimulation of the trigeminal nerve for ADHD

    Evidence-based recommendations on transcutaneous electrical stimulation of the trigeminal nerve for ADHD. This involves a single-use electrode patch stuck to the forehead, which sends small electrical pulses through the skin during sleep. Is this guidance up to date? Next review: 2026...