This guideline presents evidence and recommendations for cervical ripening and induction of labour. It aims to provide information to birth attendants and pregnant individuals on optimal perinatal care while avoiding unnecessary obstetrical intervention. Consistent interprofessional use of the guideline,...
This systematic review provides a high-quality, comprehensive summary of recommendations on hypertension (HT) and type 2 diabetes mellitus (T2DM), accentuating patient blood pressure, HbA1c levels, patterns of drug treatment, management, and screening of these diseases. The overall objective of the revie...
Gartlehner, G;
Dobrescu, A;
Chapman, A;
Toromanova, A;
Emprechtinger, R;
Persad, E;
Affengruber, L;
Pieh, C;
Klerings, I;
Wagner, G.
Primary care patients and clinicians may prefer alternative options to second-generation antidepressants for major depressive disorder (MDD). To compare the benefits and harms of nonpharmacologic treatments with second-generation antidepressants as first-step interventions for acute MDD, and to compare s...
This first update alert reports the surveillance results of the living systematic review on “Nonpharmacologic and Pharmacologic Treatments of Adult Patients With Major Depressive Disorder: A Systematic Review and Network Meta-analysis for a Clinical Guideline by the American College of Physicians” (1...
Qaseem, Amir;
Hicks, Lauri;
Etxeandia-Ikobaltzeta, Itziar;
Shamliyan, Tatyana;
Cooney, Thomas G;
Cross, J. Thomas;
Fitterman, Nick;
Lin, Jennifer S;
Maroto, Miguel;
Obley, Adam J;
Tice, Jeffrey A;
Tufte, Janice.
Osteoporosis is a disease, common in older age, that makes your bones weaker and can lead to a fracture. People with previous fractures and those who have other risk factors for fractures, including family history of fractures, vitamin D deficiency or low calcium intake, smoking, excessive alcohol intake...
Abdel Aziz, Hiba;
Bugaev, Nikolay;
Baltazar, Gerard;
Brown, Zachary;
Haines, Krista;
Gupta, Sameer;
Yeung, Lawrence;
Posluszny, Joseph;
Como, John;
Freeman, Jennifer;
Kasotakis, George.
The kidney is the most frequently injured component of the genitourinary system, accounting for 5% of all trauma cases. Several guidelines by different societies address the management of urological trauma. However, unanswered questions remain regarding optimal use of angioembolization in hemodynamically...
Evidence-based recommendations on maribavir (Livtencity) for cytomegalovirus infection in adults after transplant.
Commercial arrangement
There is a simple discount patient access scheme for maribavir. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisat...
Evidence-based recommendations on trabeculectomy with a biodegradable collagen matrix implant for glaucoma. This involves cutting a small flap in the white of the eye and putting a patch over the flap to help healing and prevent scarring. Fluid slowly drains out of the flap and the patch dissolves over t...
NICE is unable to make a recommendation on angiotensin II for treating vasosuppressor-resistant hypotension caused by septic or distributive shock. This is because Paion AG did not provide an evidence submission. We will review this decision if the company decides to make a submission....
This guidance replaces the NICE medtech innovation briefing on LiverMultiScan for liver disease (MIB181).
Your responsibility
This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expecte...
