Evidence-based recommendations on semaglutide (Wegovy) for managing overweight and obesity in adults.
Commercial availability
The Wegovy brand of semaglutide is not commercially available yet....
Evidence-based recommendations on percutaneous transluminal renal sympathetic denervation for resistant hypertension. This involves inserting a device through the skin (percutaneous) into an artery in the thigh and then into the renal arteries (transluminal). It sends radio or sound waves to destroy the ...
Evidence-based recommendations on eptinezumab (VYEPTI) for preventing migraine in adults.
Commercial arrangement
There is a simple discount patient access scheme for eptinezumab. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisations can contact United...
Evidence-based recommendations on cannabidiol (Epidyolex) for treating seizures caused by tuberous sclerosis complex.
Commercial arrangement
There is a simple discount patient access scheme for cannabidiol. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS orga...
Evidence-based recommendations on polatuzumab vedotin (Polivy) with rituximab, cyclophosphamide, doxorubicin and prednisolone for untreated diffuse large B-cell lymphoma in adults.
Commercial arrangement
There is a simple discount patient access scheme for polatuzumab vedotin. NHS organisations can get ...
Evidence-based recommendations on endoluminal gastroplication for gastro-oesophageal reflux disease. This involves an endoscopic fastening device being inserted through the mouth and into the stomach, along with an endoscope for constant visualisation. The device is used to attach the fundus to the anter...
Sandbrink, Friedhelm;
Murphy, Jennifer L;
Johansson, Melanie;
Olson, Juli L;
Edens, Ellen;
Clinton-Lont, Jamie;
Sall, James;
Spevak, Christopher;
Brown, Nicole;
Guinta, Raquel;
Macedo, Franz;
Nazario, Mitchell;
Pangarkar, Sanjog;
Preston, Samuel;
Prince, Matthew;
Real, Donna Endsley;
Riegleman, David;
Steil, Evan.
In May 2022, leadership within the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) approved a joint clinical practice guideline for the use of opioids when managing chronic pain. This synopsis summarizes the recommendations that the authors believe are the most important to ...
Singh, Siddharth;
Ananthakrishnan, Ashwin N;
Nguyen, Nghia H;
Cohen, Benjamin L;
Velayos, Fernando S;
Weiss, Jennifer M;
Sultan, Shahnaz;
Siddique, Shazia M;
Adler, Jeremy;
Chachu, Karen A.
Biomarkers are used frequently for noninvasive monitoring and treatment decision making in the management of patients with ulcerative colitis (UC). This American Gastroenterological Association (AGA) guideline is intended to support practitioners in decisions about the use of biomarkers for the managemen...
Fuxman, Claudia;
Sicilia, Beatriz;
Linares, María Eugenia;
García-López, Santiago;
Sueyro, Ramiro González;
González-Lamac, Yago;
Zabana, Yamile;
Hinojosa, Joaquín;
Barreiro-de Acosta, Manuel;
Balderramo, Domingo;
Balfour, Deborah;
Bellicoso, Maricel;
Daffra, Pamela;
Morelli, Daniela;
Orsi, Marina;
Rausch, Astrid;
Ruffinengo, Orlando;
Torok, Martín;
Sambuellir, Alicia;
Novillos, Abel;
Gomollónt, Fernando;
Paula, Juan Andrés De.
Ulcerative colitis (UC) is a chronic inflammatory disease that compromises the colon, affecting the quality of life of individuals of any age. In practice, there is a wide spectrum of clinical situations. The advances made in the physio pathogenesis of UC have allowed the development of new, more effecti...
Wang, Qiaoyu;
Tao, Hua;
Fei, Zhimin;
Wang, Shuo;
Hu, Xin;
Li, Ling;
Liu, Dong;
Tao, Xia;
Xie, Jian;
Guo, Ruichen;
Zhao, Chengson;
Wang, Rui.
We have updated the guideline for preventing and managing perioperative infection in China, given the global issues with antimicrobial resistance and the need to optimize antimicrobial usage and improve hospital infection control levels. We conducted a comprehensive evaluation of the evidence for prevent...
