This guideline covers managing lower urinary tract symptoms (LUTS) in men over 18. It aims to improve the quality of life for men with LUTS by recommending which assessments they should receive, and when conservative management, drug treatment and surgery can help. In June 2015, we reviewed the evidence for phosophodiesterase-5 inhibitors, and added recommendation 1.4.10 on when to use them. We also added research recommendation 2.5 on the clinical and cost effectiveness of phosophodiesterase-5 inhibitors in men who do not have erectile dysfunction.