This guideline covers the care of women and their babies during labour and immediately after birth. It focuses on women who give birth between 37 and 42 weeks of pregnancy (‘term’). The guideline helps women to make informed choices about where to have their baby and about their care in labour. It al...
El cáncer de próstata metastásico se presenta en el 20% de pacientes al momento del
diagnóstico de cáncer de próstata (1). Los sitios comunes de diseminación metastásica
locorregional son los ganglios linfáticos (99%) y huesos como pelvis, cadera y esqueleto axial
(84%); mientras que las localiz...
Nadee, Sarah;
Pervez, Alina;
Abid, Muhammad Abbas;
Rizvi, Nashia Ali;
Ayub, Bushra;
Ahmed, Sibtain;
Jafri, Lena;
Habib Khan, Asyha;
Haider, Adil H;
Sheikh, Aisha;
Khalid, Rehab Naeem;
Aamdani, Salima Saleem;
Mustafa, Mohsin Ali;
Riaz, Mehmood;
Irfan, Khadija;
Noordin, Shahryar;
Majid, Hafsa;
Umer, Masood;
Zehra, Nawazish.
Due to its high prevalence, we aimed to create postmenopausal osteoporosis clinical practice guideline via GRADE-ADOLOPMENT for Pakistan. We recommend a higher dose (2000-4000 IU) of vitamin D for osteoporotic patients who are old, have malabsorption, or are obese. The guideline will help standardize car...
Evidence-based recommendations on risankizumab (Skyrizi) for previously treated moderately to severely active Crohn's disease in people 16 years and over....
NICE is unable to make a recommendation on ciltacabtagene autoleucel (Carvykti) for treating relapsed or refractory multiple myeloma in adults. This is because Janssen withdrew its evidence submission for the appraisal. We will review this decision if the company decides to make a submission....
Evidence-based recommendations on difelikefalin (Kapruvia) for pruritus in adults with chronic kidney disease having haemodialysis....
Athanazio, Rodrigo Abensur;
Tanni, Suzana Erico;
Ferreira, Juliana;
Fuccio, Marcelo de;
Marostica, Paulo José Cauduro;
Ferreira, Juliana;
Dalcin, Paulo de Tarso Roth;
Esposito, Concetta;
Canan, Mariane Gonçalves Martynychen;
Coelho, Liana Sousa;
Firmida, Mônica de Cássia;
Almeida, Marina Buarque de;
Monte, Luciana de Freitas Velloso;
Souza, Edna Lúcia;
Pinto, Leonardo Araujo;
Rached, Samia Zahi;
Oliveira, Verônica Stasiak Bednarczuk de;
Riedi, Carlos Antonio;
Silva Filho, Luiz Vicente Ribeiro Ferreira da.
A fibrose cística (FC) é uma doença genética que resulta em disfunção da proteína
reguladora de condutância transmembrana da FC (CFTR), que é um canal de cloro e
bicarbonato expresso na porção apical de células epiteliais de diversos órgãos. A
disfunção dessa proteína resulta em manifest...
Amer, Marwa;
Alshahrani, Mohammed;
Arabi, Yaseen;
Al‑jedai, Ahmed;
Alshaqaq, Hassan M;
Al‑Sharydah, Abdulaziz;
Al‑Suwaidan, Faisal A;
Aljehani, Hosam;
Nouh, Thamer;
Mashbari, Hassan;
Tarazan, Nehal;
Alqahtani, Saad;
Tashkandi, Wail;
Maghrabi, Khalid;
Albugami, Muneerah;
Albugami, Muneerah;
Hashim, Samaher;
Alsubaie, Norah M;
Alsenani, Mohammad;
Algethamy, Haifa;
Alshammari, Thamir M;
Alaklabi, Ali;
Ismail, Nadia;
Altawil, Esraa S;
Elhazmi, Alyaa;
Nahhas, Ahmed;
Aljuaid, Maha;
Alsadoon, Naif;
Binbraik, Yasser;
Yuan, Yuhong;
Alhazzani, Waleed.
To develop evidence-based clinical practice guidelines on venous thromboembolism (VTE) prevention in adults with trauma in inpatient settings. The Saudi Critical Care Society (SCCS) sponsored guidelines development and included 22 multidisciplinary panel members who completed conflict-of-interest forms. ...
This guideline covers the diagnosis and management of type 1 and type 2 diabetes in children and young people aged under 18. The guideline recommends how to support children and young people and their families and carers to maintain tight control of blood glucose to reduce the long-term risks associated ...
People with BRCA mutation-positive HER2‑negative high-risk early breast cancer usually have chemotherapy followed by surgery (neoadjuvant chemotherapy), or surgery followed by chemotherapy (adjuvant chemotherapy).
Clinical trial evidence shows that, compared with placebo, olaparib after neoadjuvant or...
