La hipertensión pulmonar (HTP) es una condición clínica caracterizada por el aumento de la
presión en las arterias pulmonares, que puede resultar de diversas causas, tales como
enfermedades cardíacas, pulmonares o trastornos vasculares (1). La HTP es una enfermedad
progresiva que afecta tanto la cap...
La primera versión de esta guía fue publicada en diciembre del 2019 (1) Posteriormente, se realizó
una actualización en el 2024. Para esta nueva versión, se actualizaron las búsquedas de cada
pregunta, a excepción de aquellas preguntas que se basaron en Dictamen Preliminar de DETSIETSI (PICO 8 y 9...
Fabrizi, Elisa;
Ancidoni, Antonio;
Locuratolo, Nicoletta;
Piscopo, Paola;
Della Gatta, Francesco;
Salemme, Simone;
Pani, Sara Maria;
Marconi, Domitilla;
Vignatelli, Luca;
Sagliocca, Luciano;
Caffarra, Paolo;
Secreto, Piero;
Guaita, Antonio;
Stracciari, Andrea;
Vanacore, Nicola;
Lacorte, Eleonora.
Approximately 2 million people in Italy are currently living with dementia or mild cognitive impairment (MCI), and 4 million are involved as family members or caregivers. Considering the significant impact of dementia, the Italian Ministry of Health entrusted the Italian National Institute of Health (Ist...
Kawano-Dourado, Leticia;
Kristianslund, Eirik Klami;
Zeraatkar, Dena;
Jani, Meghna;
Makharia, Govind;
Hazlewood, Glen;
Smith, Catherine;
Jess, Tine;
Stabell, Camilla;
Schatten, Arne;
Owen, Andrew;
Gehin, Johanna;
Katsidzira, Leolin;
Weinberg, David;
Bauer-Ventura, Iazsmin;
Tugwell, Peter;
Moayyedi, Paul;
Cecchi, Ana Veronica Wolff;
Shimabuco, Andrea;
Seterelv, Siri;
Gyatt, Gordon;
Agoritsas, Thomas;
Vandvik, Per Olav.
Clinical question: In adult patients with inflammatory bowel disease, inflammatory arthritis (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis), or psoriasis taking biologic drugs, does proactive therapeutic drug monitoring (TDM) improve outcomes as compared with standard care?
Context and c...
Donà, Daniele;
Brigadoi, Giulia;
Grandinetti, Roberto;
Pedretti, Laura;
Boscarino, Giovanni;
Barbieri, Elisa;
Matera, Luigi;
Mancino, Enrica;
Bergamini, Marcello;
Gattinara, Guido Castelli;
Chiappini, Elena;
Doria, Mattia;
Galli, Luisa;
Guarino, Alfredo;
Lo Vecchio, Andrea;
Venturini, Elisabetta;
Marseglia, Gianluigi;
Verga, Maria Carmen;
Di Mauro, Giuseppe;
Principi, Nicola;
Midulla, Fabio;
Esposito, Susanna.
Community-acquired pneumonia (CAP) is an acute infection of the lung parenchyma acquired outside the hospital or other healthcare settings, typically affecting previously healthy individuals. This intersociety consensus aims to provide evidence-based recommendations for the antibiotic treatment of mild t...
Agarwal, Arnav;
Agoritsas, Thomas;
Aertgeerts, Bert;
Coyac, Frederic;
Farhoumand, Pauline Darbellay;
Demaine, Andrew;
Fog Heen, Anja;
Foroutan, Farid;
Guyatt, Gordon H;
Jha, Vivekanand;
Li, Sheyu;
Machuve, Edward,;
Nagler, Evi;
Ponte, Belen;
Rayner, Daniel;
Tunnicliffe, David J;
Vandvik, Per Olav;
Zeng, Xiaoxi.
What is the impact of sodium-glucose cotransporter-2 (SGLT-2) inhibitors on survival and on cardiovascular and kidneyoutcomes for adults living with chronic kidney disease (CKD)? Few therapies slow kidney disease progression and improve long term prognosis for adults living with CKD. SGLT-2 inhibitors ha...
This document serves as a revision to the Society of Family Planning’s 2010 guidelines, integrating literature on new techniques and research and addressing the clinical, medical, and sociolegal questions surrounding the induction of fetal asystole. Insufficient evidence exists to recommend routine ind...
Rezende, Suely M;
Neumann, Ignacio;
Angchaisuksiri, Pantep;
Awodu, Omolade;
Boban, Ana;
Cuker, Adam;
Curtin, Julie A;
Fijnvandraat, Karin;
Gouw, Samantha C;
Gualtierotti, Roberta;
Makris, Michael;
Nahuelhual, Paula;
O’Connell, Niamh;
Saxena, Renu;
Shima, Midori;
Wu, Runhui;
Rosendaal, Frits R.
Hemophilia is a rare congenital bleeding disorder that results from complete or partial deficiency of blood coagulation factor (F)VIII (hemophilia A) or FIX (hemophilia B) due to pathogenic variants in their coding genes. Hemophilia requires complex management. To date, there is no evidence-based clinica...
Tran, K-T. T;
Mai, B. H;
Ta, L;
Dao, L. V;
Tran, H. V;
Tran, M. K;
Quach, D. T;
Vu, K. T;
Ho, Q. D. D;
Vu, K. V;
Tran, T. T;
Pham, T-H. T;
Trinh, D. T;
Nguyen, V. T;
Tran, T. V;
Duong, T. H;
Bui, H. H;
Nguyen, V-H. T;
Nguyen, T. T;
Nguyen, T. D;
Nguyen, B. C;
Phan, H. Q;
Nguyen, L. C;
Nguyen, T. L;
Dao, H. V;
Thai, K. D;
Phan, N. T;
Le, N. V;
Le, L. T;
Vo, M-C. H;
Le, T-P. T;
Ho, P. T;
Le, Q. D;
Tran, P-T. P;
Dau, Q-L.
Functional dyspepsia (FD) is a common disorder in clinical practice. It is necessary to rule out physical causes to diagnose this condition. However, the diagnosis is challenging particularly in resource-limited areas. The aim of this consensus is to update international and regional guidelines on the ma...
