This guideline covers managing neuropathic pain (nerve pain) with pharmacological treatments (drugs) in adults in non-specialist settings. It aims to improve quality of life for people with conditions such as neuralgia, shingles and diabetic neuropathy by reducing pain and promoting increased participati...
The update of the treatment guide "Management of adult asthma in primary care" was initiated because five years had passed since the publication of the original guide. The procedure for updating treatment manuals is written in the "Estonian manual for the preparation of treatment manuals" (2020). At the ...
Rochwerg, Bram;
Agoritsas, Thomas;
Lamontagne, François;
Leo, Yee-Sin;
Macdonald, Helen;
Agarwal, Arnav;
Zeng, Linan;
Lytvyn, Lyubov;
Appiah, John Adabie;
Amin, Wagdy;
Arabi, Yaseen;
Blumberg, Lucille;
Burhan, Erlina;
Bausch, Frederique;
Calfee, Carolyn S;
Cao, Bin;
Cecconi, Maurizio;
Chanda, Duncan;
Cooke, Graham;
Du, Bin;
Dunning, Jake;
Geduld, Heike;
Gee, Patrick;
Hashimi, Madiha;
Hui, David S;
Kabra, Sushil;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kim, Yae-Jean;
Kissoon, Niranjan;
Kwizera, Arthur;
Laake, Jon Henrik;
Machado, Flavia R;
Mahaka, Imelda;
Manai, Hela;
Mino, Greta;
Nsutebu, Emmanuel;
Pshenichnaya, Natalia;
Qadir, Nida;
Sabzwari, Saniya;
Sarin, Rohit;
Sharland, Michael;
Shen, Yinzhong;
Ranganathan, Shalini Sri;
Souza, Joao;
Ugarte, Sebastian;
Venkatapuram, Sridhar;
Dat, Vu Quoc;
Vuyiseka, Dubula;
Wijewickrama, Ananda;
Maguire, Brittany;
Zeraatkar, Dena;
Bartoszko, Jessica;
Ge, Long;
Brignardello-Petersen, Romina;
Siemieniuk, Reed;
Guyatt, Gordon;
Diaz, Janet;
Jacobs, Michael;
Vandvik, Per Olav.
What is the role of drug interventions in the treatment of patients with covid-19? The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint publication of results from the WHO SOLIDARITY trial. It contains a weak or conditional recommendation against th...
Jin, Ying-Hui;
Zhan, Qing-Yuan;
Peng, Zhi-Yong;
Ren, Xue-Qun;
Yin, Xun-Tao;
Cai, Lin;
Yuan, Yu-Feng;
Yue, Ji-Rong;
Zhang, Xiao-Chun;
Yang, Qi-Wen;
Ji, Jianguang;
Xia, Jian;
Li, Yi-Rong;
Zhou, Fu-Xiang;
Gao, Ya-Dong;
Yu, Zhui;
Xu, Feng;
Tu, Ming-Li;
Tan, Li-Ming;
Yang, Min;
Chen, Fang;
Zhang, Xiao-Ju;
Zeng, Mei;
Zhu, Yu;
Liu, Xin-Can;
Yang, Jian;
Zhao, Dong-Chi;
Ding, Yu-Feng;
Hou, Ning;
Wang, Fu-Bing;
Chen, Hao;
Zhang, Yong-Gang;
Li, Wei;
Chen, Wen;
Shi, Yue-Xian;
Yang, Xiu-Zhi;
Wang, Xue-Jun;
Zhong, Yan-Jun;
Zhao, Ming-Juan;
Li, Bing-Hui;
Ma, Lin-Lu;
Zi, Hao;
Wang, Na;
Wang, Yun-Yun;
Yu, Shao-Fu;
Li, Lu-Yao;
Huang, Qiao;
Weng, Hong;
Ren, Xiang-Ying;
Luo, Li-Sha;
Fan, Man-Ru;
Huang, Di;
Xue, Hong-Yang;
Yu, Lin-Xin;
Gao, Jin-Ping;
Deng, Tong;
Zeng, Xian-Tao;
Li, Hong-Jun;
Cheng, Zhen-Shun;
Yao, Xiaomei;
Wang, Xing-Huan.
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness,
coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis
and treatment guidelines for clinicians caring for patients are needed. In the ...
Chimioprévention/méthodes,
Infections à coronavirus/diagnostic,
Infections à coronavirus/traitement médicamenteux,
Pneumopathie virale/diagnostic,
Pneumopathie virale/traitement médicamenteux,
Pandémies/prévention et contrôle,
Betacoronavirus/effets des médicaments et des substances chimiques,
Pratique factuelle/méthodes,
Antirétroviraux/usage thérapeutique,
Lopinavir/usage thérapeutique,
Chloroquine/usage thérapeutique,
Récepteurs à l'interleukine-6/usage thérapeutique,
Hydroxychloroquine/usage thérapeutique,
Plasma sanguin/immunologie
Rochwerg, Bram;
Agarwal, Arnav;
Zeng, Linan;
Leo, Yee-Sin;
Appiah, John Adabie;
Agoritsas, Thomas;
Bartoszko, Jessica;
Brignardello-Petersen, Romina;
Ergan, Begum;
Ge, Long;
Geduld, Heike;
Gershengorn, Hayley B;
Manai, Hela;
Huang, Minhua;
Lamontagne, François;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kurian, Linda;
Kwizera, Arthur;
Murthy, Srinivas;
Qadir, Nida;
Siemieniuk, Reed;
Silvestre, Maria Asuncion;
Vandvik, Per Olav;
Ye, Zhikang;
Zeraatkar, Dena;
Guyatt, Gordon.
Clinical question: What is the role of remdesivir in the treatment of severe covid-19? This guideline was triggered by the ACTT-1 trial published in the New England Journal of Medicine on 22 May 2020.Remdesivir has received worldwide attention as a potentially effective treatment for severe covid-19. Aft...
This guideline covers mental health rehabilitation for adults with complex psychosis. It aims to ensure people can have rehabilitation when they need it and promotes a positive approach to long-term recovery. It includes recommendations on organising rehabilitation services, assessment and care planning,...
A potentially severe acute respiratory infection caused by the novel coronavirus severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2).[1] The clinical presentation is generally that of a respiratory infection
with a symptom severity ranging from a mild common cold-like illness, to a severe viral ...
Betacoronavirus/pathogénicité,
Infections à coronavirus/imagerie diagnostique,
Infections à coronavirus/complications,
Infections à coronavirus/traitement médicamenteux,
Pneumopathie virale/imagerie diagnostique,
Pneumopathie virale/traitement médicamenteux,
Pneumopathie virale/complications,
Pandémies/statistiques et données numériques,
Aggravation transitoire des symptômes,
Groupes à Risque,
Chine/épidémiologie,
Pneumonie associée aux soins/diagnostic,
Personnel de santé/organisation et administration,
État de porteur sain/transmission,
Transmission verticale de maladie infectieuse/prévention et contrôle
Be aware of the links between mental illness and obesity, and ensure you manage the weight gain side-effects of medications used in the treatment of mental illness.
Be aware that mental illness can impact obesity management efforts, and screen patients for potential mental illnesses that need to be a...
Solari, A;
Giordano, A;
Sastre-Garriga, J;
Köpke, S;
Rahn, A. C;
Kleiter, I;
Aleksovska, K;
Battaglia, M. A;
Bay, J;
Copetti, M;
Drulovic, J;
Kooij, L;
Mens, J;
Meza Murillo, E. R;
Milanov, I;
Milo, R;
Pekmezovic, T;
Vosburgh, J;
Silber, E;
Veronese, S;
Patti, F;
Voltz, R;
Oliver, D.
Background and purpose
Patients with severe, progressive multiple sclerosis (MS) have complex physical and psychosocial needs, typically over several years. Few treatment options are available to prevent or delay further clinical worsening in this population. The objective was to develop an evidence-base...
Moores, Lisa K;
Tritschler, Tobias;
Brosnahan, Shari;
Carrier, Marc;
Collen, Jacob F;
Doerschug, Kevin;
Holley, Aaron B;
Jimenez, David;
Gal, Gregoire Le;
Rali, Parth;
Wells, Philip.
Emerging evidence shows that severe coronavirus disease 2019 (COVID-19) can be complicated by a significant coagulopathy, that likely manifests in the form of both microthrombosis and VTE. This recognition has led to the urgent need for practical guidance regarding prevention, diagnosis, and treatment of...
