Use of multiple micronutrient powders for home fortification of foods consumed by pregnant women
Publication year: 2011
Pregnant women are particularly vulnerable to vitamin and mineral deficiencies
because of the increase in metabolic demands to meet fetal requirements for growth
and development (1). Iron deficiency is the most common micronutrient deficiency
and is the leading cause of anaemia in the general population. An estimated 41.8% of
pregnant women worldwide are anaemic (2), and approximately 60% of cases in nonmalarious areas and 50% in malaria-endemic settings are assumed to be due to iron
deficiency (3). In addition to iron deficiency, pregnant women, particularly those
living in developing countries, are often deficient in multiple other nutrients (1, 4).
The causes of the high burden of maternal micronutrient deficiencies include poor
access to and consumption of foods with adequate micronutrient content, cultural
practices and infections . Vitamin and mineral deficiencies in pregnancy are associated with adverse health outcomes in both the mother and her newborn. For example, iron deficiency
accounts for 18% of maternal mortality (5) and is associated with premature delivery
and low birth weight (6). Iodine deficiency is the principal cause of preventable brain
damage in childhood (7) and leads to thyroid under-function and goitrogenesis in
adults (8). Nearly two billion people have insufficient iodine intake, and even
subclinical iodine deficiency during pregnancy increases the risk of miscarriage and
fetal growth restriction (9). Vitamin A deficiency affects approximately 19 million
pregnant women worldwide and is associated with an increased risk of complications
and death during pregnancy and in the postpartum period (10, 11). Severe vitamin A
deficiency in the mother can also lead to low amounts of vitamin A reserves in the
baby, which can negatively affect lung development and survival in the first year of
life (12, 13). Other micronutrients of concern during pregnancy are folic acid, vitamin
D, zinc and vitamin B1.