WHO recommendations on drug treatment for non-severe hypertension in pregnancy
Publication year: 2020
Hypertensive disorders of pregnancy are an
important cause of severe morbidity, long-term
disability and death among both pregnant women
and their babies, and account for approximately
14% of all maternal deaths worldwide. Improving
care for women around the time of childbirth is
a necessary step towards achievement of the
health targets of the Sustainable Development
Goals (SDGs). Efforts to prevent and reduce
morbidity and mortality during pregnancy and
childbirth could also help address the profound
inequities in maternal and perinatal health
globally. To achieve these goals, healthcare
providers, health managers, policy-makers
and other stakeholders need up-to-date and
evidence-based recommendations to inform
clinical policies and practices.
In 2019, the Executive Guideline Steering Group
(GSG) on WHO maternal and perinatal health
recommendations prioritized issuing new WHO
recommendations on antihypertensive drugs
for non-severe (mild to moderate) hypertension
during pregnancy in response to new important
evidence on this intervention. For this guideline,
non-severe hypertension and mild to moderate
hypertension is used interchangeably, defined as
diastolic blood pressure of 90–109 mmHg and/or
systolic blood pressure of 140–159 mmHg (1-3).