The primary objective of this clinical practice guideline is to provide gynaecologists with an algorithm and evidence to guide the diagnosis and management of endometrial polyps. Target population All patients with symptomatic or asymptomatic endometrial polyps. Options for management of endometrial polyps include expectant, medical, and surgical management. These will depend on symptoms, risks for malignancy, and patient choice. Outcomes include resolution of symptoms, histopathological diagnosis, and complete removal of the polyp. The implementation of this guideline aims to benefit patients with symptomatic or asymptomatic endometrial polyps and provide physicians with an evidence-based approach toward diagnosis and management (including expectant, medical, and surgical management) of polyps. The following search terms were entered into PubMed/Medline and Cochrane: endometrial polyps, polyps, endometrial thickening, abnormal uterine bleeding, postmenopausal bleeding, endometrial hyperplasia, endometrial cancer, hormonal therapy, female infertility.

All articles were included in the literature search up to 2021 and the following study types were included:

randomized controlled trials, meta-analyses, systematic reviews, observational studies, and case reports. Additional publications were identified from the bibliographies of these articles. Only English-language articles were reviewed. The authors rated the quality of evidence and strength of recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. See Appendix A (Tables A1 for definitions and A2 for interpretations of strong and weak recommendations). Gynaecologists, family physicians, registered nurses, nurse practitioners, medical students, and residents and fellows. Uterine polyps are common and can cause abnormal bleeding, infertility, or bleeding after menopause. If patients don’t experience symptoms, treatment is often not necessary. Polyps can be treated with medication but often a surgery will be necessary.