The purpose of this document is to provide a basis for advice to clinicians on the use of the currently available antivirals for patients presenting with illness due to influenza virus infection, as well their use for chemoprophylaxis. This guidance updates and replaces the recommendations published in A...

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This revised guidance is published in two parts. Part II documents the procedures followed in developing this guidance, together with a review of evidence and other new information on the pharmacological agents considered....

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Pandemic (H1N1) 2009, the first influenza pandemic of the 21st century, reached all parts of the world within a year, causing epidemics of varying magnitude. During the pandemic period, the World Health Organization (WHO) received reports of over 18 000 laboratory-confirmed deaths due to infection with t...