BIGG

International Society on Thrombosis and Haemostasis clinical practice guideline for treatment of congenital hemophilia A and B based on the Grading of Recommendations Assessment, Development, and Evaluation methodology

Rezende, Suely M; Neumann, Ignacio; Angchaisuksiri, Pantep; Awodu, Omolade; Boban, Ana; Cuker, Adam; Curtin, Julie A; Fijnvandraat, Karin; Gouw, Samantha C; Gualtierotti, Roberta; Makris, Michael; Nahuelhual, Paula; O’Connell, Niamh; Saxena, Renu; Shima, Midori; Wu, Runhui; Rosendaal, Frits R.

J. thromb. haemost; 22 (9), 2024

Hemophilia is a rare congenital bleeding disorder that results from complete or partial deficiency of blood coagulation factor (F)VIII (hemophilia A) or FIX (hemophilia B) due to pathogenic variants in their coding genes. Hemophilia requires complex management. To date, there is no evidence-based clinica...

Hemophilia A/drug therapy, Hemophilia B/drug therapy, Hemorrhage/prevention & control, Hemostatics/therapeutic use

Fulltext

Guidelines on the use of prophylactic factor replacement for children and adults with Haemophilia A and B

The writing group produced the draft guideline, which was subsequently revised by consensus. Review of the manuscript was performed by the BSH Guidelines Committee Haemostasis and Thrombosis Taskforce, the BSH Guidelines Committee and the Haemostasis and Thrombosis sounding board of the BSH. It was also ...