The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs: policy guidance
This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...
Tuberculosis, Multidrug-Resistant/diagnosis, Antibiotics, Antitubercular/pharmacology, Molecular Probe Techniques, Microbial Sensitivity Tests, Fluoroquinolones/therapeutic use, Drug Resistance, Bacterial/genetics, Genotype, Mutation, Tuberculosis, Multidrug-Resistant/genetics, Mycobacterium tuberculosis/drug effects, Mycobacterium tuberculosis/genetics