About one fourth of the world’s population is estimated to be infected with the tuberculosis (TB) bacterium, and about 5–10% of those infected develop active TB disease in their lifetime. The risk for active TB disease after infection depends on several factors, the most important being the person’...
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy provide state-of-the-art knowledge and evidence on leprosy diagnosis, treatment and prevention based on a public health approach in endemic countries. The target audience of this document includes policy-makers in leprosy or infectious...
Background
The programmatic management of latent tuberculosis infection (LTBI) in populations most at risk of developing TB remains a critical activity to disrupt Mycobacterium tuberculosis transmission, as identified in the End TB Strategy. LTBI is defined as a state of persistent immune response to sti...
Since the release of the consolidated guidelines in 2015, new evidence has emerged. Consequently, in an effort to further support countries, programme managers, health workers and other stakeholders seeking to achieve national and international HIV goals, this 2016 update issues new recommendations and a...
For over 100 years, major epidemics of meningococcal disease have occurred every few years within the African meningitis belt, which runs across the continent from Senegal to Ethiopia. The objectives of this review were to revise WHO guidelines on control of epidemic meningitis in subSaharan Africa conce...
Disease Outbreaks,
Meningitis, Bacterial/prevention & control,
Meningitis, Bacterial/drug therapy,
Africa South of the Sahara/epidemiology,
Meningitis, Bacterial/diagnosis,
Meningitis, Bacterial/epidemiology,
Meningococcal Vaccines/administration & dosage,
Antibiotic Prophylaxis/methods,
Haemophilus Vaccines/administration & dosage,
Reagent Kits, Diagnostic,
Prevalence,
Incidence,
Contact Tracing
WHO has developed guidelines on systematic screening for active tuberculosis (TB) based on a thorough review of available evidence. Early detection of TB is essential to further improve health outcomes for people with TB, and to reduce TB transmission more effectively. Systematic screening in high risk g...
Tuberculosis (TB) contacts are people who have close contact with patients with infectious TB.
As they are at high risk for infection (and in line with the Stop TB strategy), TB contacts should
be investigated systematically and actively for TB infection and disease. Such interventions
are called ‘tube...