Immunoglobulin light chain (AL) amyloidosis is a rare disease. Treatment is challenging, justified in part by systemic compromise and limited scientific evidence. Develop evidencebased recommendations that allow adequate treatment of patients with amyloidosis AL. A list of PICO format questions focused ...
This guideline covers the diagnosing and managing of myeloma (including smouldering myeloma
and primary plasma cell leukaemia) in people aged 16 and over. It aims to improve care for people
with myeloma by promoting the most effective tests and treatments for myeloma and its
complications....
Barosi, Giovanni;
Merlini, Giampaolo;
Atto, Billio;
Boccadoro, Mario;
Corradini, Paolo;
Marchetti, Monia;
Massaia, Massimo;
Tosi, Patrizia;
Palumbo, Antonio;
Cavo, Michele;
Tura, Sante.
In this project, we produced drug-specific recommendations targeting the use of new agents for multiple myeloma (MM). We used the GRADE (Grades of Recommendation, Assessment, Development, and Evaluation) system which separates the judgments on quality of evidence from the judgment about strength of recom...
Antineoplastic Combined Chemotherapy Protocols,
Antineoplastic Combined Chemotherapy Protocols/administration & dosage,
Boronic Acids/therapeutic use,
Bortezomib/therapeutic use,
Hematology/legislation & jurisprudence,
Hematology/methods,
Lenalidomide/therapeutic use,
Multiple Myeloma/pathology,
Neoplasm Grading,
Pyrazines/administration & dosage,
Societies, Medical/legislation & jurisprudence,
Thalidomide/therapeutic use
