Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released in 2018 ...
Histoplasmosis is a disease caused by the fungus Histoplasma capsulatum. This disease is highly endemic in some regions of North America, Central America, and South America and is also reported in certain countries of Asia and Africa. It often affects people with impaired immunity, including people livin...
BACKGROUND:
Voriconazole (VRZ) is a second-generation triazole antifungal agent with broad-spectrum activity. It is available in both intravenous and oral formulations, and is primarily indicated for treating invasive aspergillosis. The most commonly used dose for adults is 4 mg/kg or 200 mg twice daily....
Increasing access to antiretroviral therapy (ART) has transformed the prognosis of HIVinfected patients in resource-limited settings (RLS). However, treatment coverage remains relatively low, and HIV diagnosis occurs at a late stage. As a result, many patients continue to die of HIV-related opportunistic...
Cryptococcosis/diagnosis,
Flucytosine/administration & dosage,
Antifungal Agents/administration & dosage,
AIDS-Related Opportunistic Infections/microbiology,
Fluconazole/administration & dosage,
Amphotericin B/administration & dosage,
Cryptococcosis,
Cryptococcosis/drug therapy,
Cryptococcosis/prevention & control,
Meningitis, Cryptococcal/drug therapy,
Drug Therapy, Combination
