Evaluar la efectividad de las medidas preventivas para disminuir la aparición de nuevos casos de sobrepeso y obesidad en la población general, incluyendo niños y adultos de ambos sexos. Evaluar la efectividad y eventos adversos asociados a los diferentes tratamientos disponibles para el manejo del sob...
This guideline covers the assessment and care of adults who are at risk of or who have cardiovascular disease (CVD), such as heart disease and stroke. It aims to help healthcare professionals identify people who are at risk of cardiovascular problems including people with type 1 or type 2 diabetes, or ch...
This guideline covers optimising care for adults with multimorbidity (multiple long-term conditions) by reducing treatment burden (polypharmacy and multiple appointments) and unplanned care. It aims to improve quality of life by promoting shared decisions based on what is important to each person in term...
This guideline covers children and young people who display harmful sexual behaviour, including those on remand or serving community or custodial sentences. It aims to ensure these problems don’t escalate and possibly lead to them being charged with a sexual offence. It also aims to ensure no-one is un...
McCormack, FX;
Gupta, N;
Finlay, GR;
Young, LR;
Taveira-DaSilva, AM;
Glasgow, CG;
Steagall, WK;
Johnson, SR;
Sahn, SA;
Ryu, JH;
Strange, C;
Seyama, K;
Sullivan, EJ;
Kotloff, RM;
Downey, GP;
Chapman, JT;
Han, MK;
D'Armiento, JM;
Inoue, Y;
Henske, EP;
Bissler, JJ;
Colby, TV;
Kinder, BW;
Wikenheiser-Brokamp, KA;
Brown, KK;
Cordier, JF;
Meyer, C;
Cottin, V;
Brozek, JL;
Smith, K;
Wilson, KC;
Moss, J.
"BACKGROUND:
Lymphangioleiomyomatosis (LAM) is a rare cystic lung disease that primarily affects women. The purpose of these guidelines is to provide recommendations for the diagnosis and treatment of LAM.
METHODS:
Systematic reviews were performed to summarize evidence pertinent to our questions. The e...
Vascular Endothelial Growth Factor D,
Sirolimus/therapeutic use,
Sirolimus,
Biopsy,
Lung,
Lymphangioleiomyomatosis,
Tomography, X-Ray Computed,
Vascular Endothelial Growth Factor D/blood,
Lung/diagnostic imaging,
Lymphangioleiomyomatosis,
Lymphangioleiomyomatosis/diagnosis,
Lymphangioleiomyomatosis/therapy
Grace, SL;
Turk-Adawi, KI;
Contractor, A;
Atrey, A;
Campbell, N;
Derman, W;
Melo Ghisi, GL;
Oldridge, N;
Sarkar, BK;
Yeo, TJ;
Lopez-Jimenez, F;
Mendis, S;
Oh, P;
Hu, D;
Sarrafzadegan, N.
"OBJECTIVE:
Cardiovascular disease is a global epidemic, which is largely preventable. Cardiac rehabilitation (CR) is demonstrated to be cost-effective and efficacious in high-income countries. CR could represent an important approach to mitigate the epidemic of cardiovascular disease in lower-resource s...
Models, Organizational,
Health Resources,
Health Care Costs,
Activities of Daily Living,
Consensus,
Cardiovascular Diseases/diagnosis,
Cardiovascular Diseases,
Exercise Therapy,
Delivery of Health Care,
Cost-Benefit Analysis,
Patient Education as Topic,
Return to Work,
Risk Reduction Behavior,
Self Care,
Cardiovascular Diseases/therapy
This guideline covers preventing, assessing and managing mental health problems in people with learning disabilities in all settings (including health, social care, education, and forensic and criminal justice). It aims to improve assessment and support for mental health conditions, and help people with ...
"BACKGROUND AND OBJECTIVE:
Poor mobilization of peripheral blood stem cells (CD34(+) cells) from bone marrow is a frequent reason for not reaching the autologous stem cell trasplantation (SCT) procedure in patients diagnosed with lymphoma or myeloma. Plerixafor, a reversible inhibitor of the binding of s...
Heterocyclic Compounds,
Receptors, CXCR4,
Hematopoietic Stem Cell Mobilization,
Lymphoma,
Multiple Myeloma,
Peripheral Blood Stem Cell Transplantation,
Receptors, CXCR4/antagonists & inhibitors,
Transplantation, Autologous,
Multiple Myeloma/therapy,
Lymphoma/therapy
Fock, KM;
Talley, N;
Goh, KL;
Sugano, K;
Katelaris, P;
Holtmann, G;
Pandolfino, JE;
Sharma, P;
Ang, TL;
Hongo, M;
Wu, J;
Chen, M;
Choi, MG;
Law, NM;
Sheu, BS;
Zhang, J;
Ho, KY;
Sollano, J;
Rani, AA;
Kositchaiwat, C;
Bhatia, S.
"OBJECTIVE:
Since the publication of the Asia-Pacific consensus on gastro-oesophageal reflux disease in 2008, there has been further scientific advancement in this field. This updated consensus focuses on proton pump inhibitor-refractory reflux disease and Barrett's oesophagus.
METHODS:
A steering commi...
Zhang, Zhongheng;
Smischney, Nathan J;
Zhang, Haibo;
Poucke, Sven Van;
Tsirigotis, Panagiotis;
Rello, Jordi;
Honore, Patrick M;
Kuan, Win Sen;
Ray, Juliet June;
Zhou, Jiancang;
Shang, You;
Yu, Yuetian;
Jung, Christian;
Robba, Chiara;
Taccone, Fabio Silvio;
Caironi, Pietro;
Grimaldi, David;
Hofer, Stefan;
Dimopoulos, George;
Leone, Marc;
Hong, Sang-Bum;
Bahloul, Mabrouk;
Argaud, Laurent;
Kim, Won Young;
Spapen, Herbert D;
Rocco, Jose Rodolfo.
: Sepsis is a heterogeneous disease caused by an infection stimulus that triggers several complex
local and systemic immuno-inflammatory reactions, which results in multiple organ dysfunction and
significant morbidity and mortality. The diagnosis of sepsis is challenging because there is no gold standard...