Total: 2199

    Autism spectrum disorder in adults: diagnosis and management: Last updated 14 June 2021

    This guideline covers diagnosing and managing suspected or confirmed autism spectrum disorder (autism, Asperger's syndrome and atypical autism) in people aged 18 and over. It aims to improve access and engagement with interventions and services, and the experience of care, for people with autism....

    Autism spectrum disorder in under 19s: support and management: Last updated 14 June 2021

    The term autism describes qualitative differences and impairments in reciprocal social interaction and social communication, combined with restricted interests and rigid and repetitive behaviours, often with a lifelong impact. In addition to these features, autistic children and young people frequently e...

    2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

    Arthritis care res; 73 (7), 2021
    To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluat...

    The Use of Dexamethasone in Patients with High-Grade Gliomas

    Patients with primary brain tumours often develop vasogenic edema and increased intracranial pressure. Corticosteroid therapy improves this in most patients, generally within 48 hours. As such, corticosteroid therapy is sometimes a necessary prerequisite to embarking on chemotherapy and radiotherapy foll...

    Guidelines for the management of symptomatic sexually transmitted infections

    Worldwide, people acquire more than 1 million curable sexually transmitted infections (STIs) every day. Based on prevalence data from 2009 to 2016, in 2019, WHO published estimates of new cases of chlamydia, gonorrhoea, syphilis and trichomoniasis, showing total estimated incident cases of 376.4 million ...

    AGA technical review on the medical management of moderate to severe luminal and perianal fistulizing Crohn's disease

    Gastroenterology; 160 (7), 2021
    The incidence and prevalence of Crohn's disease (CD) is rising globally. Patients with moderate to severe CD are at high risk for needing surgery and hospitalization and for developing disease-related complications, corticosteroid dependence, and serious infections. Optimal management of outpatients with...

    Guideline No. 416: labour, delivery, and postpartum care for people with physical disabilities

    J. obstet. gynaecol. Can; 43 (6), 2021
    To describe evidence-based practice for managing the labour, delivery, and postpartum care of people with physical disabilities in Canada. This guideline addresses the needs of people with physical disabilities, with a focus on conditions that affect strength and mobility, as well as those that affect ne...

    Guideline No. 414: management of pregnancy of unknown location and tubal and nontubal ectopic pregnancies

    J. obstet. gynaecol. Can; 43 (5), 2021
    To provide an evidence-based algorithm to guide the diagnosis and management of pregnancy of unknown location and tubal and nontubal ectopic pregnancy. All patients of reproductive age. The implementation of this guideline aims to benefit patients with positive β-human chorionic gonadotropin results and...

    Guideline No. 420: cytomegalovirus Infection in Pregnancy

    J. obstet. gynaecol. Can; 43 (7), 2021
    To provide an update on current recommendations for cytomegalovirus (CMV) infection during pregnancy. The objectives of this guideline are: To improve perinatal care providers’ awareness of the consequences of maternal CMV infection for the fetus and the infant; To emphasize the importance of educating...