The field of HCV therapeutics continues to evolve rapidly and, since the World Health Organization (WHO) issued its first Guidelines for the screening, care and treatment of persons with hepatitis C infection in 2014, several new medicines have been approved by at least one stringent regulatory authority...
Objetivo: brindar una guía de práctica clínica basada en la evidencia más reciente para el diagnóstico y tratamiento de la infección por Helicobacter pylori teniendo en cuenta la efectividad y seguridad de las intervenciones dirigidas a pacientes, personal asistencial, administrativo y entes gubern...
The overall objective of the guidelines is to provide public health approach guidance on evidencebased practices for testing, treating and managing LTBI in individuals with the highest risk of progression to active disease. The guidelines are expected to provide the basis and rationale for the developmen...
Antitubercular Agents/administration & dosage,
Latent Tuberculosis/drug therapy,
Latent Tuberculosis/prevention & control,
Vulnerable Populations,
Treatment Outcome,
Medication Adherence,
Rifampin/administration & dosage,
Isoniazid/administration & dosage,
Drug Therapy, Combination,
Latent Tuberculosis/diagnosis
Malaria case management, which consists of prompt diagnosis and effective treatment, remains a vital component of malaria control and elimination strategies. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on new evidence as well as a recommend...
Raghu, Ganesh;
Rochwerg, Bram;
Zhang, Yuan;
Cuello Garcia, Carlos A;
Azuma, Arata;
Behr, Juergen;
Brozek, Jan L;
Collard, Harold R;
Cunningham, William;
Homma, Sakae;
Johkoh, Takeshi;
Martinez, Fernando J;
Myers, Jeffrey;
Protzko, Shandra L;
Richeldi, Luca;
Rind, David;
Selman, Moisés;
Theodore, Arthur;
Wells, Athol U;
Hoogsteden, Henk;
Schünemann, Holger J.
Background: This document updates the American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on idiopathic pulmonary fibrosis treatment. Methods: Systematic reviews and, when appropriate, meta-analyses were performed to summarize ...
Hepatitis C,
Antiviral Agents/therapeutic use,
Hepatitis C/diagnosis,
Liver Transplantation,
Contraindications,
Drug Monitoring,
Drug Therapy, Combination,
Interferons/therapeutic use,
Acute Disease,
Hepatitis C/etiology,
Hepatitis C/therapy,
Hepatitis C, Chronic/diagnosis,
Hepatitis C, Chronic/etiology,
Hepatitis C, Chronic/therapy
The aim of this guidance is to provide the interim principles that should guide the use of delamanid in conjunction with WHO-recommended MDR-TB treatment. It also specifies the essential treatment and management conditions for use of this drug, in particular the patient's eligibility criteria and safety ...
Cost-Benefit Analysis,
Tuberculosis, Multidrug-Resistant/drug therapy,
Drug Therapy, Combination,
Nitroimidazoles/therapeutic use,
Treatment Outcome,
Antitubercular Agents/therapeutic use,
Tuberculosis, Pulmonary/drug therapy,
Clinical Trials as Topic,
Nitroimidazoles/economics,
Antitubercular Agents/economics
This Guideline outlines the purpose and the target audience of the second edition of Guidance for national tuberculosis programmes on the management of tuberculosis in children. It discusses the difference between TB in children and adolescents and TB in adults and provides an estimate of the burden of c...
DESCRIPTION: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the screening, monitoring, and treatment of adults with stage 1 to 3 chronic kidney disease. METHODS: This guideline is based on a systematic evidence review eval...
Renal Insufficiency, Chronic/diagnosis,
Renal Insufficiency, Chronic/drug therapy,
Disease Progression,
Triage,
Angiotensin Receptor Antagonists/therapeutic use,
Angiotensin-Converting Enzyme Inhibitors/therapeutic use,
Antihypertensive Agents/therapeutic use,
Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use,
Hypolipidemic Agents/therapeutic use,
Gemfibrozil/therapeutic use,
Asymptomatic Diseases,
Drug Therapy, Combination,
GRADE Approach
Increasing access to antiretroviral therapy (ART) has transformed the prognosis of HIVinfected patients in resource-limited settings (RLS). However, treatment coverage remains relatively low, and HIV diagnosis occurs at a late stage. As a result, many patients continue to die of HIV-related opportunistic...
Cryptococcosis/diagnosis,
Flucytosine/administration & dosage,
Antifungal Agents/administration & dosage,
AIDS-Related Opportunistic Infections/microbiology,
Fluconazole/administration & dosage,
Amphotericin B/administration & dosage,
Cryptococcosis,
Cryptococcosis/drug therapy,
Cryptococcosis/prevention & control,
Meningitis, Cryptococcal/drug therapy,
Drug Therapy, Combination
