This guideline covers assessment and early management of head injury in babies, children, young people and adults. It aims to ensure that people have the right care for the severity of their head injury, including direct referral to specialist care if needed....
Evidence-based recommendations on risankizumab (Skyrizi) for previously treated moderately to severely active Crohn's disease in people 16 years and over....
NICE is unable to make a recommendation on ciltacabtagene autoleucel (Carvykti) for treating relapsed or refractory multiple myeloma in adults. This is because Janssen withdrew its evidence submission for the appraisal. We will review this decision if the company decides to make a submission....
Evidence-based recommendations on difelikefalin (Kapruvia) for pruritus in adults with chronic kidney disease having haemodialysis....
Six digitally enabled therapies can be used as treatment options for
adults with anxiety disorders while further evidence is generated on their
clinical and cost effectiveness, once they have appropriate approval.
The following technologies can only be used once they have Digital
Technology Assessment Cr...
Three digitally enabled therapies can be used as treatment options for
adults with depression while further evidence is generated on their
clinical and cost effectiveness. The therapies should be used with
support from a trained practitioner or therapist in NHS Talking Therapies
for anxiety and depressio...
Athanazio, Rodrigo Abensur;
Tanni, Suzana Erico;
Ferreira, Juliana;
Fuccio, Marcelo de;
Marostica, Paulo José Cauduro;
Ferreira, Juliana;
Dalcin, Paulo de Tarso Roth;
Esposito, Concetta;
Canan, Mariane Gonçalves Martynychen;
Coelho, Liana Sousa;
Firmida, Mônica de Cássia;
Almeida, Marina Buarque de;
Monte, Luciana de Freitas Velloso;
Souza, Edna Lúcia;
Pinto, Leonardo Araujo;
Rached, Samia Zahi;
Oliveira, Verônica Stasiak Bednarczuk de;
Riedi, Carlos Antonio;
Silva Filho, Luiz Vicente Ribeiro Ferreira da.
A fibrose cística (FC) é uma doença genética que resulta em disfunção da proteína
reguladora de condutância transmembrana da FC (CFTR), que é um canal de cloro e
bicarbonato expresso na porção apical de células epiteliais de diversos órgãos. A
disfunção dessa proteína resulta em manifest...
Amer, Marwa;
Alshahrani, Mohammed;
Arabi, Yaseen;
Al‑jedai, Ahmed;
Alshaqaq, Hassan M;
Al‑Sharydah, Abdulaziz;
Al‑Suwaidan, Faisal A;
Aljehani, Hosam;
Nouh, Thamer;
Mashbari, Hassan;
Tarazan, Nehal;
Alqahtani, Saad;
Tashkandi, Wail;
Maghrabi, Khalid;
Albugami, Muneerah;
Albugami, Muneerah;
Hashim, Samaher;
Alsubaie, Norah M;
Alsenani, Mohammad;
Algethamy, Haifa;
Alshammari, Thamir M;
Alaklabi, Ali;
Ismail, Nadia;
Altawil, Esraa S;
Elhazmi, Alyaa;
Nahhas, Ahmed;
Aljuaid, Maha;
Alsadoon, Naif;
Binbraik, Yasser;
Yuan, Yuhong;
Alhazzani, Waleed.
To develop evidence-based clinical practice guidelines on venous thromboembolism (VTE) prevention in adults with trauma in inpatient settings. The Saudi Critical Care Society (SCCS) sponsored guidelines development and included 22 multidisciplinary panel members who completed conflict-of-interest forms. ...
This guideline covers the diagnosis and management of type 1 and type 2 diabetes in children and young people aged under 18. The guideline recommends how to support children and young people and their families and carers to maintain tight control of blood glucose to reduce the long-term risks associated ...
People with BRCA mutation-positive HER2‑negative high-risk early breast cancer usually have chemotherapy followed by surgery (neoadjuvant chemotherapy), or surgery followed by chemotherapy (adjuvant chemotherapy).
Clinical trial evidence shows that, compared with placebo, olaparib after neoadjuvant or...