Evidence-based recommendations on pembrolizumab (Keytruda) plus chemotherapy with or without bevacizumab for persistent, recurrent or metastatic cervical cancer in adults....
Evidence-based recommendations on polatuzumab vedotin (Polivy) with rituximab, cyclophosphamide, doxorubicin and prednisolone for untreated diffuse large B-cell lymphoma in adults.
Commercial arrangement
There is a simple discount patient access scheme for polatuzumab vedotin. NHS organisations can get ...
The leishmaniases are a group of diseases caused by Leishmania spp., which occur in cutaneous, mucocutaneous and visceral forms. They are neglected tropical diseases (NTDs), which disproportionately affect marginalized populations who have limited access to health care. HIV co-infected patients with Leis...
Leishmaniasis, Visceral/etiology,
Drug Therapy, Combination,
HIV Infections/complications,
Anti-Retroviral Agents/therapeutic use,
Africa, Eastern,
Asia, Southeastern,
Anthelmintics/therapeutic use,
Leishmaniasis, Visceral/drug therapy,
Coinfection/complications
Salinas, Ariel;
Huaringa-Marcelo, Jorge;
Alfaro-Lozano, José;
Becerra-Chauca, Naysha;
Nieto-Gutierre, Wendy;
Garcia-Gomero, David;
De la Jara, Jesús;
Calderón-Gallegos, Julia;
Flores, Cesar;
Taype-Rondan, Alvaro;
Timaná-Ruiz, Raúl;
Salvador-Salvador, Stefany;
Carrera-Acosta, Lourdes;
Gamboa-Cárdenas, Rocío.
La Artritis Reumatoide (AR) tiene adversas consecuencias en la salud su diagnóstico temprano y manejo óptimo requiere recomendaciones basadas en evidencia de alta calidad adaptadas a cada sistema de salud. Objetivo: Proveer recomendaciones clínicas basadas en evidencia para el diagnóstico y manejo in...
More people die each year from cardiovascular diseases than from any other cause. Over three
quarters of heart disease and stroke-related deaths occur in low-income and middle-income countries.
Hypertension – or elevated blood pressure – is a serious medical condition that significantly increases the...
Lindner, Andreas K;
Lejon, Veerle;
Chappuis, François;
Seixas, Jorge;
Kazumba, Leon;
Barrett, Michael P;
Mwamba, Erick;
Erphas, Olema;
Akl, Elie A;
Villanueva, Gemma;
Bergman, Hanna;
Simarro, Pere;
Ebeja, Augustin Kadima;
Priotto, Gerardo;
Franco, Jose Ramon.
Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a parasitic infection that usually progresses to coma and death unless treated. WHO has updated its guidelines for the treatment of this infection on the basis of independent literature reviews and using the Grading of Recommendation...
Trypanosomiasis, African/drug therapy,
Trypanosoma brucei gambiense,
Pentamidine/administration & dosage,
Nifurtimox/administration & dosage,
Nitroimidazoles/administration & dosage,
Cerebrospinal Fluid/parasitology,
Drug Therapy, Combination,
Trypanocidal Agents/administration & dosage,
Eflornithine/administration & dosage,
Trypanosomiasis, African/parasitology
These guidelines aim to provide evidence-based recommendations on the care and treatment of persons diagnosed with chronic hepatitis C infection. They update the care and treatment section of the WHO Guidelines for the screening, care and treatment of persons with hepatitis C infection issued in April 20...
Hepatitis C, Chronic/complications,
Hepatitis C, Chronic/drug therapy,
HIV Infections/complications,
Hepatitis C, Chronic/diagnosis,
Coinfection,
Antiviral Agents/administration & dosage,
Drug Therapy, Combination
This guideline covers diagnosing and managing pancreatic cancer in adults aged 18 and over. It aims to improve care by ensuring quicker and more accurate diagnosis, and by specifying the most effective treatments for people depending on how advanced their cancer is....
Pancreatic Neoplasms/diagnosis,
Pancreatic Neoplasms/drug therapy,
Lymph Node Excision/methods,
Positron-Emission Tomography/methods,
Capecitabine/therapeutic use,
Paclitaxel/therapeutic use,
Albumins/therapeutic use,
Drug Therapy, Combination,
Chemotherapy, Adjuvant
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy provide state-of-the-art knowledge and evidence on leprosy diagnosis, treatment and prevention based on a public health approach in endemic countries. The target audience of this document includes policy-makers in leprosy or infectious...
Postpartum haemorrhage (PPH) is commonly defined as a blood loss of 500 ml or more within 24 hours after birth, and affects about 5% of all women giving birth around the world. The primary aim of these recommendations is to improve the quality of care and outcomes for women giving birth, as they relate t...
