A clinical summary of this KDP was published in the Journal of the Ministry of Health of the Czech Republic . More than twenty years ago, cerebrovascular accidents (CMP) were considered an incurable disease. In recent years, mainly thanks to the development of recanalization treatment and preventive strategies, there has been a significant shift in the results of care for patients with ischemic and hemorrhagic CMP. Ischemic cerebral aneurysms (iCMP) account for 88% of all CMPs, the remaining 12% are hemorrhagic CMPs. In the Czech Republic, the incidence of iCMP is currently 211 cases per 100,000 inhabitants per year, and the prevalence is estimated at 240,000 cases. The main objective of this clinical guideline is to provide recommendations for the care of adult patients with iCMP and transient ischemic attack (TIA) based on the best available evidence. The recommended procedure answers the clinical question of which interventions improve outcomes of care in patients after iCMP or TIA of non-cardioembolic etiology.