This guideline covers managing spasticity and co-existing motor disorders and their early musculoskeletal complications in children and young people (from birth up to their 19th birthday) with non-progressive brain disorders. It aims to reduce variation in practice and help healthcare professionals to select and use appropriate treatments. In November 2016, recommendation 1.1.8 was amended to update information on the World Health Organization’s International Classification of Functioning, Disability and Health (ICF) and the domains it covers.