Sterling, Timothy R;
Njie, Gibril;
Zenner, Dominik;
Cohn, David L;
Reves, Randall;
Ahmed, Amina;
Menzies, Dick;
Horsburgh, C. Robert;
Crane, Charles M;
Burgos, Marcos;
LoBue, Philip;
Winston, Carla A;
Belknap, Robert.
Comprehensive guidelines for treatment of latent tuberculosis infection (LTBI) among persons living in the United States were last published in 2000 (American Thoracic Society. CDC targeted tuberculin testing and treatment of latent tuberculosis infection. Am J Respir Crit Care Med 2000;161:S221–47). S...
Tuberculosis (TB) strains with drug resistance (DR-TB) are more difficult to treat than drug-susceptible ones, and threaten global progress towards the targets set by the End TB Strategy of the World Health Organization (WHO). There is thus a critical need for evidence-based policy recommendations on the...
This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...
Tuberculosis Resistente a Múltiples Medicamentos/diagnóstico,
Antibióticos Antituberculosos/farmacología,
Técnicas de Sonda Molecular,
Pruebas de Sensibilidad Microbiana,
Fluoroquinolonas/uso terapéutico,
Farmacorresistencia Bacteriana/genética,
Genotipo,
Mutación,
Tuberculosis Resistente a Múltiples Medicamentos/genética,
Mycobacterium tuberculosis/efectos de los fármacos,
Mycobacterium tuberculosis/genética
Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting cases earlier, including cases of smear-negative disease. This document updates existing WHO policy on the use of molecular LPAs for detecting MTBC a...
