For patients with acute respiratory insufficiency, mechanical ("invasive") ventilation is a fundamental therapeutic measure to ensure sufficient gas exchange. Despite decades of strong research efforts, central questions on mechanical ventilation therapy are still answered incompletely. Therefore, many d...
Duijts, Liesbeth;
van Meel, Evelien R;
Moschino, Laura;
Baraldi, Eugenio;
Barnhoorn, Magda;
Bramer, Wichor M;
Bolton, Charlotte E;
Boyd, Jeanette;
Buchvald, Frederik;
del Cerro, Maria Jesus;
Colin, Andrew A;
Ersu, Refika;
Greenough, Anne;
Halvorsen, Thomas;
Gremmen, Christiaan;
Kamphuis, Juliette;
Kotecha, Sailesh;
Rooney-Otero, Kathleen;
Schulzke, Sven;
Wilson, Andrew;
Rigau, David;
Morgan, Rebecca L;
Tonia, Thomy;
Roehr, Charles C;
Pijnenburg, Marielle W.
This document provides recommendations for monitoring and treatment of children in whom bronchopulmonary dysplasia (BPD) has been established and were discharged from the hospital, or who were older than 36 weeks of postmenstrual age. The guideline was based on pre-defined Population, Intervention, Com...
To develop an evidence-based clinical practice guideline for the prevention of oral mucositis in children (0-18 years) receiving treatment for cancer or undergoing haematopoietic stem cell transplantation (HSCT).
The Mucositis Prevention Guideline Development Group was interdisciplinary and included in...
Panaccione, R;
Steinhart, A. H;
Bressler, B;
Khanna, R;
Marshall, J. K;
Targownik, L;
Bitton, A;
Borgaonkr, M;
Chauhan, U;
Halloran, B;
Jones, J;
Kennedy, E;
Leontiadis, G. I;
Jr Loftus, E. V;
Meddings, J;
Moayyedi, P;
Plamondon, S.
Crohn's disease (CD) is a lifelong illness with substantial morbidity, although new therapies and treatment paradigms have been developed. We provide guidance for treatment of ambulatory patients with mild to severe active luminal CD. We performed a systematic review to identify published studies of the ...
Angeles-Han, Sheila T;
Ringold, Sarah;
Beukelman, Timothy;
Lovell, Daniel;
Cuello, Carlos A;
Becker, Mara L;
Colbert, Robert A;
Feldman, Brian M;
Holland, Gary N;
Ferguson, Polly J;
Gewanter, Harry;
Guzman, Jaime;
Horonje, Jennifer;
Nigrovic, Peter A;
Ombrello, Michael J;
Passo, Murray H;
Stoll, Matthew L;
Rabinovich, C. Egla;
Sen, H. Nida;
Schneider, Rayfel;
Halyabar, Olha;
Hays, Kimberly;
Shah, Amit Aakash;
Sullivan, Nancy;
Szymansk, Ann Marie;
Turgunbaev, Marat;
Turner, Amy;
Reston, James.
To develop recommendations for the screening, monitoring, and treatment of uveitis in children with juvenile idiopathic arthritis (JIA).Methods. Pediatric rheumatologists, ophthalmologists with expertise in uveitis, patient representatives, and methodologists generated key clinical questions to be addres...
This guideline covers interventions in the acute stage of a stroke or transient ischaemic attack
(TIA). It offers the best clinical advice on the diagnosis and acute management of stroke and TIA in
the 48 hours after onset of symptoms....
This guideline covers the management of ulcerative colitis in children, young people and adults. It
aims to help professionals to provide consistent high-quality care and it highlights the importance
of advice and support for people with ulcerative colitis....
This guideline covers the diagnosis and management of prostate cancer in secondary care,
including information on the best way to diagnose and identify different stages of the disease, and
how to manage adverse effects of treatment. It also includes recommendations on follow-up in
primary care for people...
This guideline covers diagnosing, assessing and managing primary hyperparathyroidism. It aims to
improve recognition and treatment of this condition, reducing long-term complications and
improving quality of life....
This guideline covers the initial assessment of symptoms and signs that might indicate a
neurological condition. It helps non-specialist healthcare professionals to identify people who
should be offered referral for specialist investigation....