Lehrnbecher, T;
Phillips, R;
Alexander, S;
Alvaro, F;
Carlesse, F;
Fisher, B;
Hakim, H;
Santolaya, M;
Castagnola, E;
Davis, B. L;
Dupuis, L. L;
Gibson, F;
Groll, A. H;
Gaur, A;
Gupta, A;
Kebudi, R;
Petrilli, S. L;
Steinbach, W. J;
Villarroel, M;
Zaoutis, T Sung.
To develop an evidence-based guideline for the empiric management of pediatric fever and neutropenia (FN). The International Pediatric Fever and Neutropenia Guideline Panel is a multidisciplinary and multinational group composed of experts in pediatric oncology and infectious disease as well as a patient...
Community-acquired pneumonia is diagnosed by clinical features (e.g., cough, fever, pleuritic chest pain) and by lung
imaging, usually an infiltrate seen on chest radiography. Initial evaluation should determine the need for hospitalization versus outpatient management using validated mortality or severi...
Neumonía/diagnóstico por imagen,
Neumonía/terapia,
Enfermedades Respiratorias/diagnóstico,
Atención Ambulatoria/organización & administración,
Cultivo de Sangre/instrumentación,
Macrólidos/uso terapéutico,
Doxiciclina/uso terapéutico,
Antibacterianos/uso terapéutico,
Fluoroquinolonas/uso terapéutico,
Unidades de Cuidados Intensivos,
Neumonía Asociada a la Atención Médica/prevención & control
Increasing access to antiretroviral therapy (ART) has transformed the prognosis of HIVinfected patients in resource-limited settings (RLS). However, treatment coverage remains relatively low, and HIV diagnosis occurs at a late stage. As a result, many patients continue to die of HIV-related opportunistic...
Criptococosis/diagnóstico,
Flucitosina/administración & dosificación,
Antifúngicos/administración & dosificación,
Infecciones Oportunistas Relacionadas con el SIDA/microbiología,
Fluconazol/administración & dosificación,
Anfotericina B/administración & dosificación,
Criptococosis,
Criptococosis/tratamiento farmacológico,
Criptococosis/prevención & control,
Meningitis Criptocócica/tratamiento farmacológico,
Quimioterapia Combinada
Research over the past decade has resulted in the development of two commercial interferongamma release assays (IGRAs), based on the principle that the T-cells of individuals who have acquired TB infection respond to re-stimulation with Mycobacterium tuberculosis-specific antigens by secreting interferon...
Earlier and improved tuberculosis (TB) case detection - including smear-negative disease, often associated with HIV co-infection - as well as expanded capacity to diagnose multidrug-resistant tuberculosis (MDR-TB) are global priorities for TB control. Conventional laboratory methods are slow and cumberso...
Direct sputum smear microscopy is the most widely used means for the diagnosis of pulmonary tuberculosis (TB) and is available in most primary health-care laboratories at health-centre level. Smear microscopy may, however, be costly and inconvenient for patients, who have to make multiple visits to healt...
Malaria case management remains a vital component of the malaria control strategies.
This entails early diagnosis and prompt treatment with effective antimalarial medicines.
The WHO Guidelines for the treatment of malaria, which were first published in 2006,
provide global, evidence-based recommendations...
Dengue is the most rapidly spreading mosquito-borne viral disease in the world. In the last 50 years, incidence has increased 30-fold with increasing geographic expansion to new countries and, in the present decade, from urban to rural settings. This publication is intended to contribute to prevention an...
Dengue/diagnóstico,
Dengue/terapia,
Dengue/prevención & control,
Enfermedades Endémicas/prevención & control,
Incidencia,
Dengue/epidemiología,
Control de Mosquitos/métodos,
Insectos Vectores,
Aedes,
Dengue,
Diagnóstico Diferencial,
Reservorios de Enfermedades,
Brotes de Enfermedades
These guidelines suggest methods for selecting, evaluating and implementing HIV testing technologies and strategies based on a country’s laboratory infrastructure and surveillance needs. The guidelines provide recommendations for specimen selection, collection, storage and testing, and for the selectio...
As the HIV/AIDS epidemic imposes an ever-larger burden globally, surveillance for HIV becomes more critical in order to understand the trends of the epidemic and make sound decisions on how best to respond to it. These guidelines suggest methods for selecting, evaluating and implementing HIV testing tech...
