Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American Coll...
Pottercher, Julien;
Lefort, Hugues;
Adam, Philippe;
Barbier, Oliver;
Bouzat, Pierre;
Charbit, Jonathan;
Galinski, Michel;
Garringue, Delphine;
Gauss, Tobias;
Georg, Yannick.
To provide healthcare professionals with comprehensive multidisciplinary expert recommendations for the acute care of severe limb trauma patients, both during the prehospital phase and after admission to a Trauma Centre. A consensus committee of 21 experts was formed. A formal conflict-of-interest (COI) ...
Ansai, Shin-Ichi;
Umeayashi, Yoshihiro;
Katsumata, Noriyuki;
Kato, Hiroshi;
Kadono, Takafumi;
Takai, Toshihiro;
Namiki, Takeshi;
Nakagawa, Masahiro;
Soejima, Toshinori;
Koga, Hiroshi;
Sugaya, Makoto.
In consideration of the development of treatment options for squamous cell carcinoma (SCC), the Japanese Skin Cancer Society issued the first guidelines of SCC in 2007 and revised them in 2015. Here, we report the English version of the 2020 edition of the Japanese SCC guidelines. The first half of this ...
Clinical question What are the benefits and harms of sodium-glucose cotransporter 2 (SGLT-2) inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists when added to usual care (lifestyle interventions and/or other diabetes drugs) in adults with type 2 diabetes at different risk for cardiovascular ...
Elghazaly, Hesham;
Rugo, Hope;
Azim, Hamdy;
Swain, Sandra;
Arun, Banu;
Aapro, Matti;
Perez, Edith;
Anderson, Benjamin;
Penault-Llorca, Frederique;
Conte, Pierfranco.
The management of patients with triple-negative breast cancer (TNBC) is challenging with several controversies and unmet needs. During the 12th Breast-Gynaecological & Immuno-oncology International Cancer Conference (BGICC) Egypt, 2020, a panel of 35 breast cancer experts from 13 countries voted on conse...
Shih, Robert;
Burns, Judah;
Ajam, Amna;
Broder, Joshua;
Chakraborty, Santanu;
Kendi, Tuba;
Lacy, Mary;
Ledbetter, Luke;
Lee, Ryan;
Liebeskind, David;
Pollock, Jeffrey;
Prall, Adair;
Ptak, Thomas;
Raksin, P. B;
Shaines, Matthew;
Tsiorius, John;
Utukuri, Pallavi;
Wang, Lily;
Corey, Amanda.
Head trauma (ie, head injury) is a significant public health concern and is a leading cause of morbidity and mortality in children and young adults. Neuroimaging plays an important role in the management of head and brain injury, which can be separated into acute (0-7 days), subacute (<3 months), then ch...
Allen, Brian;
Oto, Aytekin;
Akin, Oguz;
Alexander, Lauren;
Froemming, Adam;
Fulgham, Pat;
Halpern, David;
Gettle, Lori;
Maranchie, Jodi;
Patel, Bhavik;
Patlas, Michael;
Schieda, Nicola;
Solanki, Abhishek;
Turkbey, Ismail;
Venkatesan, Aradhana;
Yoo, Don;
Lockhart, Mark.
Urothelial cancer is the second most common cancer, and cause of cancer death, related to the genitourinary tract. The goals of surveillance imaging after the treatment of urothelial cancer of the urinary bladder are to detect new or previously undetected urothelial tumors, to identify metastatic disease...
Henrichsen, Tara;
Maturen, Katherine;
Robbins, Jessica;
Akin, Esma;
Ascher, Susan;
Brook, Olga;
Dassel, Mark;
Friedman, Lucas;
Learman, Lee;
Patlas, Michael;
Sadowski, Elizabeth;
Saphier, Carl;
Wasnik, Ashish;
Glanc, Phyllis.
Acute pelvic pain is a common presenting complaint in both the emergency room and outpatient settings. Pelvic pain of gynecologic origin in postmenopausal women occurs less frequently than in premenopausal women; however, it has important differences in etiology. The most common causes of postmenopausal ...
We performed systematic reviews addressing predefined clinical questions to develop recommendations with the GRADE approach regarding management of patients with overt upper gastrointestinal bleeding. We suggest risk assessment in the emergency department to identify very-low-risk patients (e.g., Glasgow...
Agarwal, Vikas;
Shah, Lubdha;
Parsons, Matthew;
Boulter, Daniel;
Cassidy, Cartert;
Hutchins, Troy;
Johnson, Jamlik-Omari;
Kendi, Tuba;
Khan, Majid;
Liebeskind, David;
Moritani, Toshio;
Ortiz, Orlando;
Reitman, Charles;
Shah, Vinil;
Snyder, Laura;
Timpone, Vincent;
Corey, Amanda.
Myelopathy is a clinical diagnosis with localization of the neurological findings to the spinal cord, rather than the brain or the peripheral nervous system, and then to a particular segment of the spinal cord. Myelopathy can be the result of primary intrinsic disorders of the spinal cord or from seconda...
