Increasing access to antiretroviral therapy (ART) has transformed the prognosis of HIVinfected patients in resource-limited settings (RLS). However, treatment coverage remains relatively low, and HIV diagnosis occurs at a late stage. As a result, many patients continue to die of HIV-related opportunistic...
Over 1000 new cases of mother-to-child transmission of the human immunodeficiency virus (HIV) occur worldwide every day, making this the main route of transmission of HIV infection in children. Vitamin A deficiency affects about 19 million pregnant women, mostly from the WHO regions of Africa and South-E...
For the first time, the elimination of mother-to-child transmission of HIV (MTCT) is now considered a realistic public health goal and an important part of the campaign to achieve the millennium development goals. The 2010 revised PMTCT recommendations are based on two key approaches; lifelong ART for HI...
WHO guidelines for ART for HIV infection in adults and adolescents were originally published in 2002, and were revised in 2003 and 2006. New evidence has emerged on when to initiate ART, optimal ART regimens, the management of HIV coinfection with tuberculosis and chronic viral hepatitis, and the managem...
HIV-infected infants frequently present with clinical symptoms in the first year of life. Without effective treatment, an estimated one third of infected infants will have died by one year of age, and about half will have died by two years of age. These treatment guidelines serve as a framework for selec...
This publication summarizes current knowledge on the methods of diagnosing HIV infection in infants and children and sets out recommendations for practice and policy. Recommendations are designed to improve clinical management of the HIV-exposed and ‑infected child, and improve programme efforts at ear...
These guidelines use a stepped care approach to treating drug dependence. This approach acknowledges that different people require different interventions around their drug use. These guidelines take a public health approach to drug use and dependence. This approach recognises that the health of one indi...
This document recommends a proactive approach to HIV testing and counselling by care providers in these settings. Offers basic operational guidance on HIV testing and counselling in settings attended by people who inject drugs (PWID)....
HIV infection can impair the nutritional status of infected children from early in life. Growth faltering and reduction in length and height often occurs even before opportunistic infections or other symptoms in almost all infected children. The content of these guidelines acknowledges that wasting and ...
These guidelines suggest methods for selecting, evaluating and implementing HIV testing technologies and strategies based on a country’s laboratory infrastructure and surveillance needs. The guidelines provide recommendations for specimen selection, collection, storage and testing, and for the selectio...
