Total: 736

    Meningitis outbreak response in sub-Saharan Africa: WHO guideline

    For over 100 years, major epidemics of meningococcal disease have occurred every few years within the African meningitis belt, which runs across the continent from Senegal to Ethiopia. The objectives of this review were to revise WHO guidelines on control of epidemic meningitis in subSaharan Africa conce...

    The use of molecular line probe assays for the detection of resistance to isoniazid and rifampicin

    Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting cases earlier, including cases of smear-negative disease. This document updates existing WHO policy on the use of molecular LPAs for detecting MTBC a...

    The use of loop-mediated isothermal amplification (TB-LAMP) for the diagnosis of pulmonary tuberculosis: policy guidance

    Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting patients earlier, particularly patients with smear-negative TB disease. This document provides a pragmatic summary of the evidence and recommendation...

    Guideline: Infant feeding in areas of Zika virus transmission

    Zika virus is a mosquito-borne virus transmitted by Aedes mosquitoes; the same mosquito also transmits other vector-borne diseases – dengue, chikungunya and yellow fever. Purpose of the guideline The purpose of this guideline is to provide a recommendation to guide governments, ministries of health, po...

    The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs: policy guidance

    This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...

    The use of delamanid in the treatment of multidrug-resistant tuberculosis: interim policy guidance

    The aim of this guidance is to provide the interim principles that should guide the use of delamanid in conjunction with WHO-recommended MDR-TB treatment. It also specifies the essential treatment and management conditions for use of this drug, in particular the patient's eligibility criteria and safety ...

    The use of delamanid in the treatment of multidrug-resistant tuberculosis in children and adolescents: interim policy guidance

    The specific objectives were to evaluate the harms to benefits ratio of delamanid in combination with the currently recommended MDR-TB treatment regimen in children. Based on this evaluation, to develop recommendations on the use of delamanid as part of WHO-recommended longer MDR-TB treatment regimens, a...

    Guidelines on the Management of Latent Tuberculosis Infection

    The overall objective of the guidelines is to provide public health approach guidance on evidencebased practices for testing, treating and managing LTBI in individuals with the highest risk of progression to active disease. The guidelines are expected to provide the basis and rationale for the developmen...

    Guideline: sugars intake for adults and children

    The objective of this guideline is to provide recommendations on the intake of free sugars to reduce the risk of NCDs in adults and children, with a particular focus on the prevention and control of unhealthy weight gain and dental caries. The recommendations in this guideline can be used by policy-make...

    Rehabilitation in health systems

    Rehabilitation is a set of interventions designed to optimize functioning and reduce disability in individuals with health conditions in interaction with their environment. The objective of these recommendations is to provide evidence-based, expert-informed recommendations to guide governments and other...