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Evidence-based recommendations on nivolumab (Opdivo) with platinum- and fluoropyrimidine-based chemotherapy for untreated HER2-negative advanced gastric, gastro-oesophageal junction or oesophageal adenocarcinoma in adults.
Commercial arrangement
There is a commercial access agreement for nivolumab...
Evidence-based recommendations on transcutaneous electrical stimulation of the trigeminal nerve for ADHD. This involves a single-use electrode patch stuck to the forehead, which sends small electrical pulses through the skin during sleep.
Is this guidance up to date?
Next review: 2026...
Evidence-based recommendations on percutaneous image-guided cryoablation of peripheral neuroma for chronic pain. This involves using a needle-like probe to freeze and destroy small parts of nerves in neuromas to stop the pain signals.
Is this guidance up to date?
Next review: 2026...
Evidence-based recommendations on mobocertinib (EXKIVITY) for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy in adults.
Commercial arrangement
There is a simple discount patient access scheme for mobocertinib. NHS organisations ca...
Evidence-based recommendations on upadacitinib (Rinvoq) for treating moderately to severely active ulcerative colitis in adults.
Commercial arrangement
There is a simple discount patient access scheme for upadacitinib. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. ...
The American Society of Addiction Medicine (ASAM) and the American Academy of
Addiction Psychiatry (AAAP) developed this Clinical Practice Guideline on the Management
of Stimulant Use Disorder (hereafter referred to as the Guideline) to provide evidence-based
strategies and standards of care for the trea...
Now that the majority of people living with HIV take combination antiretroviral therapy (ART), the
spectrum of causes of pyrexia of unknown origin (PUO) has changed compared with the pre-ART era.
In these guidelines, we focus on causes and evaluation of PUO among people living with HIV with
CD4 counts <3...
Barbosa, Alexandre Naime;
Chebabo, Alberto;
Pérez, Clevy;
Cunha, Clóvis Arns;
Luna, David de;
Nunes, Estevão Portela;
Zambrano, Gabriela;
Ferreira, Juliana Carvalho;
Croda, Júlio;
Falavigna, Maicon;
Silva, Monica Maria Gomes da;
Cimerman, Sergio;
Parahiba, Suena Medeiros;
Tanni, Suzana;
Bernardo, Wanderley Marques;
Rodriguez-Morales, Alfonso J.
Since the beginning of the COVID-19 pandemic, therapeutic options for treating COVID-19 have been investigated at different stages of clinical manifestations. Considering the particular impact of COVID-19 in the Americas, this document aims to present recommendations for the pharmacological treatment of ...
Neumann, Ignacio;
Izcovich, Ariel;
Aguilar, Ricardo;
Basantes, Guillermo León;
Casais, Patricia;
Colorio, Cecilia C;
Esposito, María Cecilia Guillermo;
Lázaro, Pedro P. García;
Pereira, Jaime;
García, Luis A. Meillon;
Rezende, Suely Meireles;
Serrano, Juan Carlos;
Valle, Mario L. Tejerina;
Altuna, Diana;
Zúñiga, Pamela;
Vera, Felipe;
Karzulovic, Lorena;
Schünemann, Holger J.
Implementation of international guidelines in Latin American settings requires additional considerations (ie, values and preferences, resources, accessibility, feasibility, and impact on health equity). The purpose of this guideline is to provide evidence-based recommendations about the diagnosis of veno...
Complementary feeding, defined as the
process of providing foods in addition to
milk when breast milk or milk formula
alone are no longer adequate to meet
nutritional requirements, generally starts
at age 6 months and continues until
23 months of age, although breastfeeding
may continue beyond this perio...
