Resultados: 119

    The use of molecular line probe assays for the detection of resistance to isoniazid and rifampicin

    Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting cases earlier, including cases of smear-negative disease. This document updates existing WHO policy on the use of molecular LPAs for detecting MTBC a...

    The use of loop-mediated isothermal amplification (TB-LAMP) for the diagnosis of pulmonary tuberculosis: policy guidance

    Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting patients earlier, particularly patients with smear-negative TB disease. This document provides a pragmatic summary of the evidence and recommendation...

    Guideline: Infant feeding in areas of Zika virus transmission

    Zika virus is a mosquito-borne virus transmitted by Aedes mosquitoes; the same mosquito also transmits other vector-borne diseases – dengue, chikungunya and yellow fever. Purpose of the guideline The purpose of this guideline is to provide a recommendation to guide governments, ministries of health, po...

    The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs: policy guidance

    This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...

    The use of delamanid in the treatment of multidrug-resistant tuberculosis in children and adolescents: interim policy guidance

    The specific objectives were to evaluate the harms to benefits ratio of delamanid in combination with the currently recommended MDR-TB treatment regimen in children. Based on this evaluation, to develop recommendations on the use of delamanid as part of WHO-recommended longer MDR-TB treatment regimens, a...

    WHO guideline on the use of safety-engineered syringes for intramuscular, intradermal and subcutaneous injections in health care settings

    Injections are one of the most common health care procedures. Every year at least 16 billion injections are administered worldwide. The vast majority around 90% are given in curative care. Immunization injections account for around 5% of all injections, with the remaining covering other indications, incl...

    Myeloma: diagnosis and management - update information

    This guideline covers the diagnosing and managing of myeloma (including smouldering myeloma and primary plasma cell leukaemia) in people aged 16 and over. It aims to improve care for people with myeloma by promoting the most effective tests and treatments for myeloma and its complications. This guideline...

    AME evidence series 001: The Society for Translational Medicine: clinical practice guidelines for diagnosis and early identification of sepsis in the hospital

    : Sepsis is a heterogeneous disease caused by an infection stimulus that triggers several complex local and systemic immuno-inflammatory reactions, which results in multiple organ dysfunction and significant morbidity and mortality. The diagnosis of sepsis is challenging because there is no gold standard...

    The management of diabetic foot: a clinical practice guideline by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine

    J. vasc. surg; 62 (2), 2016
    Diabetes mellitus continues to grow in global prevalence and to consume an increasing amount of health care resources. One of the key areas of morbidity associated with diabetes is the diabetic foot. To improve the care of patients with diabetic foot and to provide an evidence-based multidisciplinary man...

    End of life care for infants, children and young people with life-limiting conditions: planning and management - update information

    This guideline covers the planning and management of end of life and palliative care in for infants, children and young people (aged 0–17 years) with life-limiting conditions. It aims to involve children, young people and their families in decisions about their care, and improve the support that is ava...