Alvaro, Domenico;
Hassan, Cesare;
Carpino, Guido;
Fabris, Luca;
Gringeri, Enrico;
Granata, Vincenza;
Mutignani, Massimiliano;
Morement, Helen;
Guglielmi, Alfredo;
Ridola, Lorenzo;
Marzioni, Marco;
Grazi, Gianluca;
Guido, Maria;
Cardinale, Vincenzo;
Giuliante, Felice;
Giulio, Emilio Di;
Tonini, Giuseppe;
Pantano, Francesco;
Venere, Rosanna;
Bragazzi, Maria Consiglia;
Biancanello, Francesca;
Faccioli, Jessica;
Giannetti, Aurora;
Cintolo, Marcello;
Giunta, Michela Di;
Gambato, Martina;
Lasagni, Alberto;
Izzo, Francesco;
Avallone, Antonio;
Banales, Jesus;
Rossi, Massimo;
Laghi, Andrea;
D'amati, Giulia;
Mancino, Maria Grazia;
Ridola, Lorenzo;
Catalano, Carlo.
Cholangiocarcinoma (CCA) is the second most common primary liver cancer, characterized by a poor prognosis and resistance to chemotherapeutics. The progressive increase in CCA incidence and mortality registered worldwide in the last two decades and the need to clarify various aspects of clinical manageme...
Kaufman, John A;
Barnes, Geoffrey D;
Chaer, Rabih A;
Cuschieri, Joseph;
Eberhardt, Robert T;
Johnson, Matthew S;
Kuo, William T;
Murin, Susan;
Patel, Sheena;
Rajasekhar, Anita;
Weinberg, Ido;
Gillespie, David L.
To provide evidence-based recommendations on the use of inferior vena cava (IVC) filters in the treatment of patients with or at substantial risk of venous thromboembolic disease. A multidisciplinary expert panel developed key questions to address in the guideline, and a systematic review of the literatu...
Wu, Lei;
Chen, Yaolong;
Ma, Yanfang;
Yang, Zifeng;
Yang, Nan;
Denga, Wenze;
Chen, Yuanbin;
Sun, Yuanyuan;
Li, Yimin;
Lin, Lin.
Influenza is a major public health problem worldwide. Mutations and resistance development make the use of antiviral therapy challenging. Chinese patent medicines are often used to treat influenza in China and well tolerable. However, the misuse of Chinese patent medicines is common. We therefore aimed t...
Miller, R. E;
Leary, A;
Scott, C. L;
Serra, V;
Lord , C. J;
Bowtell, D;
Chang, D. K;
Garsed, D. W;
Jonkers, J;
Ledermann, J. A;
Nik-Zainal, S;
Ray-Coquard, I;
Shah, S. P;
Matias-Guiu, X;
Swisher, E. M;
Yates, L. R.
The European Society for Medical Oncology (ESMO) Translational Research and Precision Medicine Working Group identified that there is currently uncertainty within the oncology community surrounding the different methods for HRD testing in HGSC. To address this, a collaborative project was launched with a...
O'Malley, Patrick G;
Arnold, Michael J;
Pharm, Cathy Kelley;
Spacek, Lance;
Buelt, Andrew;
Natarajan, Sundar;
Donahue, Mark P;
Vagichev, Elena;
Ballard-Hernandez, Jennifer;
Logan, Amanda;
Thomas, Lauren;
Ritter, Joan;
Neubauer, Brian E;
Downs, John R.
In June 2020, the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) released a joint update of their clinical practice guideline for managing dyslipidemia to reduce cardiovascular disease risk in adults. This synopsis describes the major recommendations. The guideline panel de...
Timsit, Jean-François;
Baleine, Julien;
Bernard, Louis;
Calvino-Gunther, Silvia;
Darmon, Michael;
Dellamonica, Jean;
Desruennes, Eric;
Leone, Marc;
Lepape, Alain;
Leroy, Olivier;
Lucet, Jean-Christophe;
Merchaoui, Zied;
Mimoz, Olivier;
Misset, Benoit;
Parienti, Jean-Jacques;
Quenot, Jean-Pierre;
Roch, Antoine;
Schmidt, Matthieu;
Slama, Michel;
Souweine, Bertrand;
Zahar, Jean-Ralph;
Zingg, Walter;
Bodet-Contentin, Laetitia;
Maxime, Virginie.
The French Society of Intensive Care Medicine (SRLF), jointly with the French-Speaking Group of Paediatric Emer‑
gency Rooms and Intensive Care Units (GFRUP) and the French-Speaking Association of Paediatric Surgical Inten‑
sivists (ADARPEF), worked out guidelines for the management of central venous...
Rochwerg, Bram;
Agoritsas, Thomas;
Lamontagne, François;
Leo, Yee-Sin;
Macdonald, Helen;
Agarwal, Arnav;
Zeng, Linan;
Lytvyn, Lyubov;
Appiah, John Adabie;
Amin, Wagdy;
Arabi, Yaseen;
Blumberg, Lucille;
Burhan, Erlina;
Bausch, Frederique;
Calfee, Carolyn S;
Cao, Bin;
Cecconi, Maurizio;
Chanda, Duncan;
Cooke, Graham;
Du, Bin;
Dunning, Jake;
Geduld, Heike;
Gee, Patrick;
Hashimi, Madiha;
Hui, David S;
Kabra, Sushil;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kim, Yae-Jean;
Kissoon, Niranjan;
Kwizera, Arthur;
Laake, Jon Henrik;
Machado, Flavia R;
Mahaka, Imelda;
Manai, Hela;
Mino, Greta;
Nsutebu, Emmanuel;
Pshenichnaya, Natalia;
Qadir, Nida;
Sabzwari, Saniya;
Sarin, Rohit;
Sharland, Michael;
Shen, Yinzhong;
Ranganathan, Shalini Sri;
Souza, Joao;
Ugarte, Sebastian;
Venkatapuram, Sridhar;
Dat, Vu Quoc;
Vuyiseka, Dubula;
Wijewickrama, Ananda;
Maguire, Brittany;
Zeraatkar, Dena;
Bartoszko, Jessica;
Ge, Long;
Brignardello-Petersen, Romina;
Siemieniuk, Reed;
Guyatt, Gordon;
Diaz, Janet;
Jacobs, Michael;
Vandvik, Per Olav.
What is the role of drug interventions in the treatment of patients with covid-19? The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint publication of results from the WHO SOLIDARITY trial. It contains a weak or conditional recommendation against th...
Jin, Ying-Hui;
Zhan, Qing-Yuan;
Peng, Zhi-Yong;
Ren, Xue-Qun;
Yin, Xun-Tao;
Cai, Lin;
Yuan, Yu-Feng;
Yue, Ji-Rong;
Zhang, Xiao-Chun;
Yang, Qi-Wen;
Ji, Jianguang;
Xia, Jian;
Li, Yi-Rong;
Zhou, Fu-Xiang;
Gao, Ya-Dong;
Yu, Zhui;
Xu, Feng;
Tu, Ming-Li;
Tan, Li-Ming;
Yang, Min;
Chen, Fang;
Zhang, Xiao-Ju;
Zeng, Mei;
Zhu, Yu;
Liu, Xin-Can;
Yang, Jian;
Zhao, Dong-Chi;
Ding, Yu-Feng;
Hou, Ning;
Wang, Fu-Bing;
Chen, Hao;
Zhang, Yong-Gang;
Li, Wei;
Chen, Wen;
Shi, Yue-Xian;
Yang, Xiu-Zhi;
Wang, Xue-Jun;
Zhong, Yan-Jun;
Zhao, Ming-Juan;
Li, Bing-Hui;
Ma, Lin-Lu;
Zi, Hao;
Wang, Na;
Wang, Yun-Yun;
Yu, Shao-Fu;
Li, Lu-Yao;
Huang, Qiao;
Weng, Hong;
Ren, Xiang-Ying;
Luo, Li-Sha;
Fan, Man-Ru;
Huang, Di;
Xue, Hong-Yang;
Yu, Lin-Xin;
Gao, Jin-Ping;
Deng, Tong;
Zeng, Xian-Tao;
Li, Hong-Jun;
Cheng, Zhen-Shun;
Yao, Xiaomei;
Wang, Xing-Huan.
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness,
coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the world. Diagnosis
and treatment guidelines for clinicians caring for patients are needed. In the ...
Quimioprevención/métodos,
Infecciones por Coronavirus/diagnóstico,
Infecciones por Coronavirus/tratamiento farmacológico,
Neumonía Viral/diagnóstico,
Neumonía Viral/tratamiento farmacológico,
Pandemias/prevención & control,
Betacoronavirus/efectos de los fármacos,
Práctica Clínica Basada en la Evidencia/métodos,
Antirretrovirales/uso terapéutico,
Lopinavir/uso terapéutico,
Cloroquina/uso terapéutico,
Receptores de Interleucina-6/uso terapéutico,
Hidroxicloroquina/uso terapéutico,
Plasma/inmunología
Rochwerg, Bram;
Agarwal, Arnav;
Zeng, Linan;
Leo, Yee-Sin;
Appiah, John Adabie;
Agoritsas, Thomas;
Bartoszko, Jessica;
Brignardello-Petersen, Romina;
Ergan, Begum;
Ge, Long;
Geduld, Heike;
Gershengorn, Hayley B;
Manai, Hela;
Huang, Minhua;
Lamontagne, François;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kurian, Linda;
Kwizera, Arthur;
Murthy, Srinivas;
Qadir, Nida;
Siemieniuk, Reed;
Silvestre, Maria Asuncion;
Vandvik, Per Olav;
Ye, Zhikang;
Zeraatkar, Dena;
Guyatt, Gordon.
Clinical question: What is the role of remdesivir in the treatment of severe covid-19? This guideline was triggered by the ACTT-1 trial published in the New England Journal of Medicine on 22 May 2020.Remdesivir has received worldwide attention as a potentially effective treatment for severe covid-19. Aft...
To establish national standards of care for screening and counselling pregnant women and women of child-bearing age about alcohol consumption and possible alcohol use disorder based on current best evidence. Health care providers who care for pregnant women and women of child-bearing age. Pregnant women ...
