Fabrizi, Elisa;
Ancidoni, Antonio;
Locuratolo, Nicoletta;
Piscopo, Paola;
Della Gatta, Francesco;
Salemme, Simone;
Pani, Sara Maria;
Marconi, Domitilla;
Vignatelli, Luca;
Sagliocca, Luciano;
Caffarra, Paolo;
Secreto, Piero;
Guaita, Antonio;
Stracciari, Andrea;
Vanacore, Nicola;
Lacorte, Eleonora.
Approximately 2 million people in Italy are currently living with dementia or mild cognitive impairment (MCI), and 4 million are involved as family members or caregivers. Considering the significant impact of dementia, the Italian Ministry of Health entrusted the Italian National Institute of Health (Ist...
Kawano-Dourado, Leticia;
Kristianslund, Eirik Klami;
Zeraatkar, Dena;
Jani, Meghna;
Makharia, Govind;
Hazlewood, Glen;
Smith, Catherine;
Jess, Tine;
Stabell, Camilla;
Schatten, Arne;
Owen, Andrew;
Gehin, Johanna;
Katsidzira, Leolin;
Weinberg, David;
Bauer-Ventura, Iazsmin;
Tugwell, Peter;
Moayyedi, Paul;
Cecchi, Ana Veronica Wolff;
Shimabuco, Andrea;
Seterelv, Siri;
Gyatt, Gordon;
Agoritsas, Thomas;
Vandvik, Per Olav.
Clinical question: In adult patients with inflammatory bowel disease, inflammatory arthritis (rheumatoid arthritis, spondyloarthritis, psoriatic arthritis), or psoriasis taking biologic drugs, does proactive therapeutic drug monitoring (TDM) improve outcomes as compared with standard care?
Context and c...
Donà, Daniele;
Brigadoi, Giulia;
Grandinetti, Roberto;
Pedretti, Laura;
Boscarino, Giovanni;
Barbieri, Elisa;
Matera, Luigi;
Mancino, Enrica;
Bergamini, Marcello;
Gattinara, Guido Castelli;
Chiappini, Elena;
Doria, Mattia;
Galli, Luisa;
Guarino, Alfredo;
Lo Vecchio, Andrea;
Venturini, Elisabetta;
Marseglia, Gianluigi;
Verga, Maria Carmen;
Di Mauro, Giuseppe;
Principi, Nicola;
Midulla, Fabio;
Esposito, Susanna.
Community-acquired pneumonia (CAP) is an acute infection of the lung parenchyma acquired outside the hospital or other healthcare settings, typically affecting previously healthy individuals. This intersociety consensus aims to provide evidence-based recommendations for the antibiotic treatment of mild t...
Agarwal, Arnav;
Agoritsas, Thomas;
Aertgeerts, Bert;
Coyac, Frederic;
Farhoumand, Pauline Darbellay;
Demaine, Andrew;
Fog Heen, Anja;
Foroutan, Farid;
Guyatt, Gordon H;
Jha, Vivekanand;
Li, Sheyu;
Machuve, Edward,;
Nagler, Evi;
Ponte, Belen;
Rayner, Daniel;
Tunnicliffe, David J;
Vandvik, Per Olav;
Zeng, Xiaoxi.
What is the impact of sodium-glucose cotransporter-2 (SGLT-2) inhibitors on survival and on cardiovascular and kidneyoutcomes for adults living with chronic kidney disease (CKD)? Few therapies slow kidney disease progression and improve long term prognosis for adults living with CKD. SGLT-2 inhibitors ha...
Strbian, Daniel;
Tsivgoulis, Georgios;
Ospel, Johanna;
Räty, Silja;
Cimflova, Petra;
Georgiopoulos, Georgios;
Ullberg, Teresa;
Arquizan, Caroline;
Gralla, Jan;
Zelenak, Kamil;
Hussain, Salman;
Fiehler, Jens;
Michel, Patrik;
Turc, Guillaume;
van Zwam, Wim H.
The aim of the present European Stroke Organisation (ESO) guideline is to provide evidence-based recommendations on the acute management of patients with basilar artery occlusion (BAO). These guidelines were prepared following the Standard Operational Procedure of the ESO and according to the GRADE metho...
Jiao, Fuyong;
Pan, Yan;
Du, Zhongdong;
Deng, Fangming;
Yang, Xiaodong;
Wang, Hong;
Shen, Jie;
Xiang, Wei;
Mu, Zhilong;
Gao, Chunyan;
Bai, Jinmei.
Kawasaki disease (KD) is a pyretic ailment predominantly observed in children aged below 5 years. There is currently a dearth of precise markers for timely identification of incomplete Kawasaki disease (IKD). It is imperative to develop updated, comprehensive, and evidence-based guidelines to effectively...
These guidelines aim to provide evidence-based recommendations for the supplementation of Vitamin D in maintaining bone health. An unmet need persists in Latin American regarding the availability of clinical and real-world data for rationalizing the use of vitamin D supplementation. The objective of thes...
De Simone, Belinda;
Chouillard, Elie;
Podda, Mauro;
Pararas, Nikolaos;
Duarte, Gustavo de Carvalho;
Fugazzola, Paola;
Birindelli, Arianna;
Coccolini, Federico;
Polistena, Andrea;
Sibilla, Maria Grazia;
Kruger, Vitor;
Fraga, Gustavo P;
Montori, Giulia;
Russo, Emanuele;
Pintar, Tadeja;
Ansaloni, Luca;
Avenia, Nicola;
Di Saverio, Salomone;
Leppäniemi, Ari;
Lauretta, Andrea;
Sartelli, Massimo;
Puzziello, Alessandro;
Carcoforo, Paolo;
Agnoletti, Vanni;
Bissoni, Luca;
Isik, Arda;
Kluger, Yoram;
Moore, Ernest E;
Romeo, Oreste Marco;
Abu-Zidan, Fikri M;
Beka, Solomon Gurmu;
Weber, Dieter G;
Tan, Edward C. T. H;
Paolillo, Ciro;
Cui, Yunfeng;
Kim, Fernando;
Picetti, Edoardo;
Di Carlo, Isidoro;
Toro, Adriana;
Sganga, Gabriele;
Sganga, Federica;
Testini, Mario;
Di Meo, Giovanna;
Kirkpatrick, Andrew W;
Marzi, Ingo;
déAngelis, Nicola;
Kelly, Michael Denis;
Wani, Imtiaz;
Sakakushev, Boris;
Bala, Miklosh;
Bonavina, Luigi;
Galante, Joseph M;
Shelat, Vishal G;
Cobianchi, Lorenzo;
Dal Mas, Francesca;
Pikoulis, Manos;
Damaskos, Dimitrios;
Coimbra, Raul;
Dhesi, Jugdeep;
Hoffman, Melissa Red;
Stahel, Philip F;
Maier, Ronald V;
Litvin, Andrey;
Latifi, Rifat;
Biffl, Walter L;
Catena, Fausto.
The trauma mortality rate is higher in the elderly compared with younger patients. Ageing is associated with physiological changes in multiple systems and correlated with frailty. Frailty is a risk factor for mortality in elderly trauma patients. We aim to provide evidence-based guidelines for the manage...
Kroese, Tiuri E;
Bronzwaer, Sebastiaan;
van Rossum, Peter S. N;
Schoppman, Sebastian F;
Deseyne, Pieter R. A. J;
van Cutsem, Eric;
Haustermans, Karin;
Nafteux, Philippe;
Thomas, Melissa;
Obermannova, Radka;
Mortensen, Hanna R;
Nordsmark, Marianne;
Pfeiffer, Per;
Elme, Anneli;
Adenis, Antoine;
Piessen, Guillaume;
Bruns, Christiane J;
Lordick, Florian;
Gockel, Ines;
Moehler, Markus;
Gani, Cihan;
Liakakos, Theodore;
Reynolds, John V;
Morganti, Alessio G;
Rosati, Riccardo;
Castoro, Carlo;
Cellini, Francesco;
D'Ugo, Domenico;
Roviello, Franco;
Bencivenga, Maria;
Manzoni, Giovanni de;
van Berge Henegouwen, Mark I;
Hulshof, Maarten C. C. M;
van Dieren, Jolanda;
Vollebergh, Marieke;
van Sandick, Johanna W;
Jeene, Paul;
Muijs, Christel;
Slingerland, Marije;
Voncken, Francine E. M;
Hartgrink, Henk;
Creemers, Geert-Jan;
van der Sangen, Maurice J. C;
Nieuwenhuijzen, Grard A. P;
Berbee, Maaike;
Verheij, Marcel;
Wijnhoven, Bas;
Beerepoot, Laurens V;
Mohammad, Nadia Haj;
Mook, Stella;
Ruurda, Jelle P;
Kolodziejczyk, Piotr;
Polkowski, Wojciech P;
Wyrwicz, Lucjan;
Alsina, Maria;
Tabernero, Josep;
Per, Manuel;
Kanonnikoff, Tania F;
Cervantes, Andrés;
Nilsson, Magnus;
Monig, Stefan;
Wagner, Anna D;
Guckenberger, Matthias;
Griffiths, Ewen A;
Smyth, Elizabeth;
Hanna, George B;
Markar, Sheraz;
Chaudry, M. Asif;
Hawkins, Maria A;
Cheong, Edward;
van Laarhoven, Hanneke W. M;
van Hillegersberg, Richard.
The OligoMetastatic Esophagogastric Cancer (OMEC) project aims to provide clinical practice guidelines for the definition, diagnosis, and treatment of esophagogastric oligometastatic disease (OMD).
Guidelines were developed according to AGREE II and GRADE principles. Guidelines were based on a systematic...
Zaffaroni, Gloria;
Mannucci, Alessandro;
Koskenvuo, Laura;
de Lacy, Borja;
Maffioli, Anna;
Bisseling, Tanya;
Half, Elizabeth;
Cavestro, Giulia Martina;
Valle, Laura;
Ryan, Neil;
Aretz, Stefan;
Brown, Karen;
Buttitta, Francesco;
Carneiro, Fatima;
Claber, Oonagh;
Blanco-Colino, Ruth;
Collard, Maxime;
Crosbie, Emma;
Cunha, Miguel;
Doulias, Triantafyllos;
Fleming, Christina;
Heinrich, Henriette;
Hüneburg, Robert;
Metras, Julie;
Nagtegaal, Iris;
Negoi, Ionut;
Nielsen, Maartje;
Pellino, Gianluca;
Ricciardiello, Luigi;
Sagir, Abdurrahman;
Sánchez-Guillén, Luis;
Seppälä, Toni T;
Siersema, Peter;
Striebeck, Benedikt;
Sampson, Julian R;
Latchford, Andrew;
Parc, Yann;
Burn, John;
Möslein, Gabriela.
Hereditary adenomatous polyposis syndromes, including familial adenomatous polyposis and other rare adenomatous polyposis syndromes, increase the lifetime risk of colorectal and other cancers.
A team of 38 experts convened to update the 2008 European recommendations for the clinical management of patient...
