BIGG

International Society on Thrombosis and Haemostasis clinical practice guideline for treatment of congenital hemophilia A and B based on the Grading of Recommendations Assessment, Development, and Evaluation methodology

Rezende, Suely M; Neumann, Ignacio; Angchaisuksiri, Pantep; Awodu, Omolade; Boban, Ana; Cuker, Adam; Curtin, Julie A; Fijnvandraat, Karin; Gouw, Samantha C; Gualtierotti, Roberta; Makris, Michael; Nahuelhual, Paula; O’Connell, Niamh; Saxena, Renu; Shima, Midori; Wu, Runhui; Rosendaal, Frits R.

J. thromb. haemost; 22 (9), 2024

Hemophilia is a rare congenital bleeding disorder that results from complete or partial deficiency of blood coagulation factor (F)VIII (hemophilia A) or FIX (hemophilia B) due to pathogenic variants in their coding genes. Hemophilia requires complex management. To date, there is no evidence-based clinica...

Hemofilia A/tratamiento farmacológico, Hemofilia B/tratamiento farmacológico, Hemorragia/prevención & control, Hemostáticos/uso terapéutico

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McMaster RARE-Bestpractices clinical practice guideline on diagnosis and management of the catastrophic antiphospholipid syndrome

Background The McMaster RARE-Bestpractices project group selected the catastrophic antiphospholipid syndrome (CAPS) for a pilot exercise in guideline development for a rare disease. Objectives The objectives of this exercise were to provide a proof of principle that guidelines can be developed for rare d...