Clinical question: What is the role of medical cannabis or cannabinoids for people living with chronic pain due to cancer or non-cancer causes?
Current practice: Chronic pain is common and distressing and associated with considerable socioeconomic burden globally. Medical cannabis is increasingly used t...
Rochwerg, Bram;
Agoritsas, Thomas;
Lamontagne, François;
Leo, Yee-Sin;
Macdonald, Helen;
Agarwal, Arnav;
Zeng, Linan;
Lytvyn, Lyubov;
Appiah, John Adabie;
Amin, Wagdy;
Arabi, Yaseen;
Blumberg, Lucille;
Burhan, Erlina;
Bausch, Frederique;
Calfee, Carolyn S;
Cao, Bin;
Cecconi, Maurizio;
Chanda, Duncan;
Cooke, Graham;
Du, Bin;
Dunning, Jake;
Geduld, Heike;
Gee, Patrick;
Hashimi, Madiha;
Hui, David S;
Kabra, Sushil;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kim, Yae-Jean;
Kissoon, Niranjan;
Kwizera, Arthur;
Laake, Jon Henrik;
Machado, Flavia R;
Mahaka, Imelda;
Manai, Hela;
Mino, Greta;
Nsutebu, Emmanuel;
Pshenichnaya, Natalia;
Qadir, Nida;
Sabzwari, Saniya;
Sarin, Rohit;
Sharland, Michael;
Shen, Yinzhong;
Ranganathan, Shalini Sri;
Souza, Joao;
Ugarte, Sebastian;
Venkatapuram, Sridhar;
Dat, Vu Quoc;
Vuyiseka, Dubula;
Wijewickrama, Ananda;
Maguire, Brittany;
Zeraatkar, Dena;
Bartoszko, Jessica;
Ge, Long;
Brignardello-Petersen, Romina;
Siemieniuk, Reed;
Guyatt, Gordon;
Diaz, Janet;
Jacobs, Michael;
Vandvik, Per Olav.
What is the role of drug interventions in the treatment of patients with covid-19? The latest version of this WHO living guidance focuses on remdesivir, following the 15 October 2020 preprint publication of results from the WHO SOLIDARITY trial. It contains a weak or conditional recommendation against th...
Rochwerg, Bram;
Agarwal, Arnav;
Zeng, Linan;
Leo, Yee-Sin;
Appiah, John Adabie;
Agoritsas, Thomas;
Bartoszko, Jessica;
Brignardello-Petersen, Romina;
Ergan, Begum;
Ge, Long;
Geduld, Heike;
Gershengorn, Hayley B;
Manai, Hela;
Huang, Minhua;
Lamontagne, François;
Kanda, Seema;
Kawano-Dourado, Leticia;
Kurian, Linda;
Kwizera, Arthur;
Murthy, Srinivas;
Qadir, Nida;
Siemieniuk, Reed;
Silvestre, Maria Asuncion;
Vandvik, Per Olav;
Ye, Zhikang;
Zeraatkar, Dena;
Guyatt, Gordon.
Clinical question: What is the role of remdesivir in the treatment of severe covid-19? This guideline was triggered by the ACTT-1 trial published in the New England Journal of Medicine on 22 May 2020.Remdesivir has received worldwide attention as a potentially effective treatment for severe covid-19. Aft...
FitzGerald, John D;
Dalbeth, Nicola;
Mikuls, Ted;
Brignardello‐Petersen, Romina;
Guyatt, Gordon;
Abeles, Aryeh M;
Gelber, Allan C;
Harrold, Leslie R;
Khanna, Dinesh;
King, Charles;
Levy, Gerald;
Libbey, Caryn;
Mount, David;
Pillinger, Michael H;
Rosenthal, Ann;
Singh, Jasvinder A;
Sims, James Edward;
Smith, Benjamin J;
Wenger, Neil S;
Bae, Sangmee Sharon;
Danve, Abhijeet;
Khanna, Puja P;
Kim, Seoyoung C;
Lenert, Aleksander;
Poon, Samuel;
Qasim, Anila;
Sehra, Shiv T;
Sharma, Tarun Sudhir Kumar;
Toprover, Michael;
Turgunbaev, Marat;
Zeng, Linan;
Zhang, Mary Ann;
Turner, Amy S;
Neogi, Tuhina.
To provide guidance for the management of gout, including indications for and optimal use of urate- lowering therapy (ULT), treatment of gout ares, and lifestyle and other medication recommendation Fifty- seven population, intervention, comparator, and outcomes questions were developed, followed by a ...
