The guideline covers diagnosing, treating and managing epilepsy and seizures in children, young people and adults in primary and secondary care. It offers best practice advice on managing epilepsy to improve health outcomes so that people with epilepsy can fully participate in daily life.
MHRA advice o...
Clinical question What are the benefits and harms of sodium-glucose cotransporter 2 (SGLT-2) inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists when added to usual care (lifestyle interventions and/or other diabetes drugs) in adults with type 2 diabetes at different risk for cardiovascular ...
Esta guía de práctica clínica, en cuya elaboración se siguió el método GRADE, tiene por objeto proveer recomendaciones para el manejo de pacientes adultos críticos con COVID-19 atendidos en las unidades de cuidados intensivos. Ofrece recomendaciones basadas en evidencia para la identificación de ...
Manejo de Atención al Paciente,
Cuidados Críticos,
COVID-19/diagnóstico por imagen,
COVID-19/complicaciones,
COVID-19/tratamiento farmacológico,
SARS-CoV-2/efectos de los fármacos,
Antirretrovirales/uso terapéutico,
Américas/epidemiología,
Factores de Riesgo,
Ventiladores Mecánicos,
Plasma/inmunología,
Antibacterianos/uso terapéutico,
Factores Inmunológicos/uso terapéutico
Elghazaly, Hesham;
Rugo, Hope;
Azim, Hamdy;
Swain, Sandra;
Arun, Banu;
Aapro, Matti;
Perez, Edith;
Anderson, Benjamin;
Penault-Llorca, Frederique;
Conte, Pierfranco.
The management of patients with triple-negative breast cancer (TNBC) is challenging with several controversies and unmet needs. During the 12th Breast-Gynaecological & Immuno-oncology International Cancer Conference (BGICC) Egypt, 2020, a panel of 35 breast cancer experts from 13 countries voted on conse...
Miravitlles, Marc;
Calle, Myriam;
Molina, Jesús;
Almagro, Pere;
Gómez, José-Tomás;
Trigueros, Juan Antonio;
Cosío, Borja G;
Casanova, Ciro;
López-Camposb, José Luis;
Riescob, Juan Antonio;
Simonetl, Pere;
Rigau, David;
Soriano, Joan B;
Ancochea, Julio;
Soler-Cataluña, Juan José.
The Spanish COPD Guidelines (GesEPOC) were first published in 2012, and since then have undergone a series of updates incorporating new evidence on the diagnosis and treatment of COPD. GesEPOC was drawn up in partnership with scientific societies involved in the treatment of COPD and the Spanish Patients...
El cáncer de próstata es producto de una proliferación descontrolada de células glandulares,
ductales u otras de la glándula prostática. El tipo histológico más frecuente es el
adenocarcinoma y se ubican principalmente en la zona periférica de la próstata (1). Así mismo,
esta neoplasia se pued...
Shih, Robert;
Burns, Judah;
Ajam, Amna;
Broder, Joshua;
Chakraborty, Santanu;
Kendi, Tuba;
Lacy, Mary;
Ledbetter, Luke;
Lee, Ryan;
Liebeskind, David;
Pollock, Jeffrey;
Prall, Adair;
Ptak, Thomas;
Raksin, P. B;
Shaines, Matthew;
Tsiorius, John;
Utukuri, Pallavi;
Wang, Lily;
Corey, Amanda.
Head trauma (ie, head injury) is a significant public health concern and is a leading cause of morbidity and mortality in children and young adults. Neuroimaging plays an important role in the management of head and brain injury, which can be separated into acute (0-7 days), subacute (<3 months), then ch...
Allen, Brian;
Oto, Aytekin;
Akin, Oguz;
Alexander, Lauren;
Froemming, Adam;
Fulgham, Pat;
Halpern, David;
Gettle, Lori;
Maranchie, Jodi;
Patel, Bhavik;
Patlas, Michael;
Schieda, Nicola;
Solanki, Abhishek;
Turkbey, Ismail;
Venkatesan, Aradhana;
Yoo, Don;
Lockhart, Mark.
Urothelial cancer is the second most common cancer, and cause of cancer death, related to the genitourinary tract. The goals of surveillance imaging after the treatment of urothelial cancer of the urinary bladder are to detect new or previously undetected urothelial tumors, to identify metastatic disease...
Henrichsen, Tara;
Maturen, Katherine;
Robbins, Jessica;
Akin, Esma;
Ascher, Susan;
Brook, Olga;
Dassel, Mark;
Friedman, Lucas;
Learman, Lee;
Patlas, Michael;
Sadowski, Elizabeth;
Saphier, Carl;
Wasnik, Ashish;
Glanc, Phyllis.
Acute pelvic pain is a common presenting complaint in both the emergency room and outpatient settings. Pelvic pain of gynecologic origin in postmenopausal women occurs less frequently than in premenopausal women; however, it has important differences in etiology. The most common causes of postmenopausal ...
We performed systematic reviews addressing predefined clinical questions to develop recommendations with the GRADE approach regarding management of patients with overt upper gastrointestinal bleeding. We suggest risk assessment in the emergency department to identify very-low-risk patients (e.g., Glasgow...