Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive th...
This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...
Tuberculosis Resistente a Múltiples Medicamentos/diagnóstico,
Antibióticos Antituberculosos/farmacología,
Técnicas de Sonda Molecular,
Pruebas de Sensibilidad Microbiana,
Fluoroquinolonas/uso terapéutico,
Farmacorresistencia Bacteriana/genética,
Genotipo,
Mutación,
Tuberculosis Resistente a Múltiples Medicamentos/genética,
Mycobacterium tuberculosis/efectos de los fármacos,
Mycobacterium tuberculosis/genética
Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting cases earlier, including cases of smear-negative disease. This document updates existing WHO policy on the use of molecular LPAs for detecting MTBC a...
Munns, CF;
Shaw, N;
Kiely, M;
Specker, BL;
Thacher, TD;
Ozono, K;
Michigami, T;
Tiosano, D;
Mughal, MZ;
Mäkitie, O;
Ramos-Abad, L;
Ward, L;
DiMeglio, LA;
Atapattu, N;
Cassinelli, H;
Braegger, C;
Pettifor, JM;
Seth, A;
Idris, HW;
Bhatia, V;
Fu, J;
Goldberg, G;
Sävendahl, L;
Khadgawat, R;
Pludowski, P;
Maddock, J;
Hyppönen, E;
Oduwole, A;
Frew, E;
Aguiar, M;
Tulchinsky, T;
Butler, G;
Högler, W.
"BACKGROUND:
Vitamin D and calcium deficiencies are common worldwide, causing nutritional rickets and osteomalacia, which have a major impact on health, growth, and development of infants, children, and adolescents; the consequences can be lethal or can last into adulthood. The goals of this evidence-bas...
This guideline covers the diagnosing and managing of myeloma (including smouldering myeloma and primary plasma cell leukaemia) in people aged 16 and over. It aims to improve care for people with myeloma by promoting the most effective tests and treatments for myeloma and its complications. This guideline...
Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting patients earlier, particularly patients with smear-negative TB disease. This document provides a pragmatic summary of the evidence and recommendation...
Ballarín Castán, José Aurelio;
García López, Fernando;
Ibeas López, José;
Juárez Vela, Raúl;
Ortega Marlasca, Manuel María;
Pequeño Saco, Sandra;
Pérez Contreras, Francisco Javier;
Pérez Maraver, Manuel;
Rigau Comas, David;
Ruiz Hidalgo, Domingo;
anabria Uribe, Andrea Juliana;
Saracho Rotaeche, Ramón.
Objetivos: Esta GPC sobre Enfermedad Renal Crónica (ERC) responde a preguntas clínicas concernientes a su detección precoz, derivación a atención especializada y manejo, tanto mediante tratamiento farmacológico como con medidas higiénico dietéticas, estilos de vida e intervenciones educativas. As...
Insuficiencia Renal Crónica/diagnóstico,
Insuficiencia Renal Crónica/terapia,
Ultrasonografía/métodos,
Inhibidores de la Enzima Convertidora de Angiotensina/uso terapéutico,
Antihipertensivos/uso terapéutico,
Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico,
Enfoque GRADE,
Estilo de Vida,
Dieta Hiposódica,
Dieta con Restricción de Proteínas,
Antagonistas de Receptores de Angiotensina/uso terapéutico
This Rapid Advice Guideline updates the Interim Guidance on the “Assessment of infants with microcephaly in the context of Zika virus” published in February 2016 (WHO/ZIKV/MOC/16.3). The recommendations provides guidance on the screening, clinical assessment, neuroimaging, laboratory investigation an...
Following the publication of Guidelines on certification of elimination of human onchocerciasis in 2001 by the World Health Organization (WHO), these are the first evidence-based guidelines developed by NTD Department according to the international standards. They provide a set of recommendations that wo...
The field of HCV therapeutics continues to evolve rapidly and, since the World Health Organization (WHO) issued its first Guidelines for the screening, care and treatment of persons with hepatitis C infection in 2014, several new medicines have been approved by at least one stringent regulatory authority...