This guideline covers identifying and managing familial hypercholesterolaemia (FH), a specific type of high cholesterol that runs in the family, in children, young people and adults. It aims to help identify people at increased risk of coronary heart disease as a result of having FH.
In October 2019, we...
Helsingen, Lise M;
Vandvik, Per Olav;
Jodal, Henriette C;
Agoritsas, Thomas;
Lytvyn, Lyubov;
Anderson, Joseph C;
Auer, Reto;
Murphy, Silje Bjerkelund;
Almadi, Majid Abdulrahman;
Corley, Douglas A;
Quinlan, Casey;
Fuchs, Jonathan M;
McKinnon, Annette;
Qaseem, Amir;
Heen, Anja Fog;
Siemieniuk, Reed A C;
Kalager, Mette;
Usher-Smith, Juliet A;
Lansdorp-Vogelaar, Iris;
Bretthauer, Michael;
Guyatt, Gordon.
Recent 15-year updates of sigmoidoscopy screening trials provide new evidence on the effectiveness of colorectal cancer screening. Prompted by the new evidence, we asked: “Does colorectal cancer screening make an important difference to health outcomes in individuals initiating screening at age 50 to 7...
Kokudo, Norihiro;
Takemura, Nobuyuki;
Hasegawa, Kiyoshi;
Takayama, Tadatoshi;
Kubo, Shoji;
Shimada, Mitsuo;
Nagano, Hiroaki;
Hatano, Etsuro;
Izumi, Namiki;
Kaneko, Shuichi;
Kudo, Masatoshi.
The fourth version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of evidence-based medicine and partly to the Grading of Recommendations Assessment, Development, and Evaluation system, which was published in Octob...
This guideline covers investigating and managing gastro-oesophageal reflux disease (GORD) and dyspepsia in people aged 18 and over. It aims to improve the treatment of GORD and dyspepsia by making detailed recommendations on Helicobacter pylori eradication, and specifying when to consider laparoscopic fu...
Shroff, Rukshana;
Calder, Francis;
Bakkaloglu, Sevcan;
Nagler, Evi V;
Stuart, Sam;
Stronach, Lynsey;
P. Schmitt, Claus;
H. Heckert, Karl;
Bourquelot, Pierre;
Wagner, Ann-Marie;
Paglialonga, Fabio;
Mitra, Sandip;
Stefanidis, Constantinos J.
There are three principle forms of vascular access available for the treatment of children with end stage kidney
disease (ESKD) by haemodialysis: tunnelled catheters placed in a central vein (central venous lines, CVLs), arteriovenous fistulas (AVF), and arteriovenous grafts (AVG) using prosthetic orbiol...
This guideline covers care for women of any age (including girls and young women under 18) who request an abortion. It aims to improve the organisation of services and make them easier for women to access. Detailed recommendations on conducting abortions at different gestational stages are also included,...
This guideline covers recognising, diagnosing and managing attention deficit hyperactivity disorder
(ADHD) in children, young people and adults. It aims to improve recognition and diagnosis, as well
as the quality of care and support for people with ADHD.
In September 2019 we amended the recommendation o...
Generar recomendaciones basadas en la mejor evidencia disponible acerca del manejo de personas
con cáncer de ovario....
Ergan, B;
Oczkowski, S;
Rochwerg, B;
Carlucci, A;
Chatwin, M;
Clini, E;
Elliott, M;
Gonzalez-Bermejo, J;
Hart, N;
Lujan, M;
Nasilowski, J;
Nava, S;
Pepin, J. L;
Pisani, L;
Storre, J. H;
Wijkstra, P;
Tonia, T;
Boyd, J;
Scala, R;
Windisch, W.
While the role of acute non-invasive ventilation (NIV) has been shown to improve outcome in acute life-threatening hypercapnic respiratory failure in COPD, the evidence of clinical efficacy of long-term home NIV (LTH-NIV) for management of COPD is less. This document provides evidence-based recommendatio...
Holguin, Fernando;
Cardet, Juan Carlos;
Chung, Kian Fan;
Diver, Sarah;
Ferreira, Diogenes S;
Fitzpatrick, Anne;
Gaga, Mina;
Kellermeye, Liz;
Khurana, Sandhya;
Knight, Shandra;
McDonald, Vanessa M;
Morgan, Rebecca L;
Ortega, Victor E;
Rigau, David;
Subbarao, Padmaja;
Tonia, Thomy;
Adcock, Ian M;
Bleecker, Eugene R;
Brightling, Chris;
Boulet, Louis-Philippe;
Cabana, Michael;
Castro, Mario;
Hamerlijnck, Dominique;
Jarjour, Nizar;
Konno, Satoshi;
Shen, Huahao;
Vitary, Cathy;
Bush, Andy.
This document provides clinical recommendations for the management of severe asthma. Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the Task Force's questions. The evidence was appraised using the Grading of Recommendations, Asses...
